Levantamento de fitoterápicos manipulados em farmácias magistrais de Dourados-MS

Abstract

RESUMO:Este trabalho teve como objetivo realizar o levantamento dos fitoterápicos manipulados em duas farmácias magistrais de Dourados, enfatizando a constituição das fórmulas (matéria-prima e forma farmacêutica), a possível indicação terapêutica, a origem das drogas vegetais utilizadas na manipulação dos fitocomplexos e a confirmação da existência ou não de artigos científicos que comprovem a utilização das cinco matérias-primas mais manipuladas nas farmácias. Para isso, foram analisados os cadastros ou fichas de pesagem, após a autorização das farmacêuticas responsáveis, do período correspondente a 21 de dezembro de 2006 a 21 de março de 2007. Concluiu-se que: 1. As matérias-primas mais utilizadas, nas duas farmácias, foram Ginkgo biloba e Hypericum perforatum, coincidentemente, com as maiores demandas e as mesmas concentrações. 2. A credibilidade nos fitoterápicos, por parte da população e dos médicos prescritores, pode ser considerada como baixa, uma vez que apenas 4,1% das fórmulas manipuladas nas duas farmácias magistrais em estudo corresponderam aos fitoterápicos. 3. Em relação às formas farmacêuticas, houve prevalência de cápsulas gelatinosas, provavelmente, porque a indicação terapêutica das fórmulas tenha sido para uso interno. 4. Dentre as cinco plantas medicinais mais manipuladas, apenas Hoodia gordonii não apresentou comprovação científica e 5. As plantas medicinais mais utilizadas na manipulação dos fitocomplexos estiveram relacionadas com a perda de peso.Unitermos: Fitoterapia, formas farmacêuticas, manipulação, fitocomplexos. ABSTRACT:The aim of this work was to carry out the survey of the phytotherapics manipulated in two magistral drugstores from Dourados, emphasizing the constitution of formulas (raw materials and pharmaceutical form), the possible therapeutic indication, the origin of the vegetal drugs utilized in manipulation of phytocomplexes and the confirmation of the existence or not of scientific articles demonstrating the use of the five most manipulated raw materials in drugstores. Thus, the registration or files weighing were analyzed, with the approval of responsible pharmacists, from the period of 21 st December 2006 to 21 st March 2007. It was concluded that: 1. Raw materials most utilized in both drugstores were Ginkgo biloba and Hypericum perforatum, coincidentally both showed the highest demands and the same concentrations. 2. The credibility of the phytotherapics, by the public and prescribers, can be considered low, since just 4.1% of the manipulated formulas from both magistral drugstores studied corresponded to the phytotherapics. 3. In relation to the pharmaceutical formulas, there was a prevalence of gelatin capsules, probably because the therapeutic indication of formulas had been designed for internal use. 4. Among the five most manipulated medicinal plants, only Hoodia gordonii did not show scientific proof and 5. The medicinal plants most utilized in the manipulation of phytocomplexes were related to weight loss.

Medicinal plants profile used by the 3rd District population of Maceió-AL

“…This is due to the cat that the interpretation of this concept represents for a share of the population, the absence of chemicals, which would be those that can cause some damage or otherwise represent danger to people's health (Vieira et al, 2010;Santana et al, 2016).…”

Efficacy and Safety of Medicinal Plants or Related Natural Products for Fibromyalgia: A Systematic Review

“…Butler (2008) [11] conducted an extensive research on the drugs approved by the Food and Drug Administration (FDA, USA) in the last decade and described that about 40% of new drugs originate from natural products. Although the application of medicinal plants in treatments around the world has suffered a strong advance, there are still a few studies that prove the safe and effective use of various plants [12]. Notable progress has been made in the recent years in the development of natural therapies, but there is an urgent need to discover effective and potent analgesic agents [13].…”

Co-processed extracts of Cassia angustifolia Vahl, Fabaceae, and Maytenus ilicifolia (Schrad.) Planch., Celastraceae, for production of high load tablets

“…The ease of manufacturing, low cost, convenience of administration and accurate dosing capabilities make tablets a popular and versatile dosage form (Gohel & Jogani, 2005). Nevertheless, the most common vehicles for medicinal plants are capsules and oral liquids (Vieira et al, 2010).…”