The article considers the basic theoretical principles, methods and approaches for designing the integrated management system of industrial, fire, environmental and emergency safety of organizations (SMIS). It is shown that for development of all subsystems SMIS it is expedient to apply the processes “Plan-Do-Check-Act” (PDCA) and procedure of process approach applied in ISO. It is also proposed to build graphical diagrams for each process and operation SMIS design in accordance with the basic provisions of the IDEF0 methodology. Application of the above methods will allow the most effective distribution of resources, functional duties and responsibilities of personnel in the overall management system of the organization.