The 2019 novel coronavirus pandemic has not only created massive public health issues, it has also produced excessive psychological disorders in healthcare professionals, including radiology staff. The aim of this study is to assess the risk perception and mental health of radiology staff in Saudi Arabia during the COVID-19 pandemic. The researcher asked radiology staff to complete an online Google Forms questionnaire, between June 10, 2020 and June 17, 2020, which contained demographic data and self-designed questions related to anxiety, insomnia, depressive symptoms, and mental health services during the pandemic. A total of 168 radiology staff participated in the study. The results indicated that 53.05% and 57.14% of the participants were experiencing mild to severe symptoms of anxiety and depression, respectively. Moreover, 47.02% of the participants were experiencing insomnia symptoms. Among all the participants, only 16.61% had received psychological materials from their hospital during the pandemic, while 22.02% had accessed online psychological assistance techniques. The health of roughly one-third (30.95%) of the participants was worse than it had been before the pandemic. COVID-19 is a source of mental health disorders for healthcare professionals, particularly radiology staff. The findings of this study indicate that more than 70% of radiology staff in Saudi Arabia are concerned about insufficient protective measures and the risk of infection. In addition, a large percentage of them have experienced mental health disorders, such as anxiety, insomnia, and depression. Regular mental healthcare services are required to decrease the negative impact of the pandemic and enhance the overall mental health of the radiology staff.