Level of D-dimer And C- Reactive Protein among Covid-19 Patients in Relation to Different Ages And Genders

Abstract

coronavirus disease of 2019 (COVID-19) is a new infectious disease spreading worldwide rapidly. COVID-19 has been associated with a risk of thrombosis, which an increase in the level of D-dimer can detect. D-dimer is a small fragment of protein present in the blood after blood clot degradation. This research aimed to evaluate the level of D-Dimer and C-reactive protein in COVID-19 patients and ascertain the relation of these markers with age and gender. From December 2020 to January 2021, patients with laboratory reports of Covid-19 were retrospectively enrolled in different hospitals and private laboratories. We collected 253 cases of the D-dimer test for different ages and genders and 204 cases of C-reactive protein test with D-dimer to detect the severity of the disease. An increased level of Ddimer of more than 0.5 mcg/ml was reported in 105 patients (41.5%). According to gender, 43.7% of males and 38.79% of females have elevated D-dimer levels. In patients with COVID-19, D-dimer levels greater than 0.5mcg/mL could accurately predict in-hospital morbidity and mortality. Therefore, D-dimer has been proposed as a possible early and effective marker for improved management of COVID-19 patients.