Levels of anxiety and depression as predictors of mortality following myocardial infarction: A 5-year follow-up

Hosseini, Seyed Hamzeh; Ghaemian, Ali; Mehdizadeh, Elaheh; Ashraf, Haleh

doi:10.5603/cj.a2014.0023

Cited by 28 publications

(40 citation statements)

References 38 publications

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“…In Lancon et al’s 34 study, the mean score of STAI was 43.7. Hosseini et al 35 , 36 proved that in 145 (50.9%) patients, the points of STAI equaled ≥40. In the examination carried out by Remröd et al, 37 the level of anxiety understood as a state equaled 38.0±12.2, while the level of anxiety understood as a trait was 36.5±11.9.…”

Section: Discussionmentioning

confidence: 97%

The level of emotion control, anxiety, and self-efficacy in the elderly in Bialystok, Poland

Cybulski¹,

Cybulski²,

Krajewska-Kułak³

et al. 2017

CIA

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PurposeThe aim of the study was to assess the level of emotion control, anxiety, and self-efficacy in the inhabitants of Bialystok (Poland) aged above 60.Patients and methodsThe study included 300 people above the age of 60, inhabitants of Bialystok and its neighborhoods: 100 residents of public nursing home, 100 participants of the University of the Third Age in Bialystok, and 100 students of the University of Healthy Senior. The three standardized psychometric scales were used in the study: Courtauld Emotional Control Scale (CECS), State-Trait Anxiety Inventory (STAI), and General Self-Efficacy Scale (GSES).ResultsThe median of the overall score of CECS equaled 54 points, which is considered average in terms of negative emotions acceptance. The mean score of perceiving anxiety as the condition of STAI (X1) was 48 points, while anxiety as a trait of STAI (X2) was 49 points. The overall score for GSES proved that respondents had a subjective feeling of self-efficacy at the level of 29 points out of 40 points possible, which means that their self-efficacy was rather at the high level in their self-assessment. In women, a negative correlation was revealed between the sense of self-efficacy and age (r=−0.320, P<0.001). Analyzing the study group affiliation of respondents, a negative correlation was reported between the sense of self-efficacy and age among the elderly residents of public nursing home (r=−0.408, P<0.001). Taking into consideration the study group affiliation of respondents, a positive correlation between anger control (CECS) and the sense of anxiety as a trait of STAI (X2) was found among participants of the University of Healthy Senior (r=0.307, P=0.002).ConclusionThe social and demographic features (gender, group affiliation, age) analyzed in the study were found to be correlated significantly with the control of negative emotions, the level of anxiety, and self-efficacy. The study group affiliation was a key variable conditioning the relations between the analyzed features. The elderly residents of public nursing home belonged to the group distinguishing negatively compared to other two study groups. The study respondents were characterized by the relatively high perception of anxiety, which may be as a result of the health and social problem present in this age group. In order to improve the quality of life, the study population should reduce level of perceived anxiety and increase the control of negative emotions and self-efficacy by social integration of seniors. The study scores in the scale of CECS, STAI, and GSES do not deviate from the world norms obtained by other researchers in the rest of the world.

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Section: Discussionmentioning

confidence: 97%

The level of emotion control, anxiety, and self-efficacy in the elderly in Bialystok, Poland

Cybulski¹,

Cybulski²,

Krajewska-Kułak³

et al. 2017

CIA

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“…Pathologically, MI results in immediate tissue damage due to myocardial ischemia, followed by biochemical changes triggered by reperfusion and pathological remodeling, leading to left ventricular (LV) heart failure and mortality45. However, despite greater understanding of the pathological processes of MI and the use of pharmacological interventions made in recent decades, post-MI mortality remains high; a 5-year survival rate is about 66.70%67. Therefore, novel interventional strategies to prevent ischemia/reperfusion (I/R) injury and pathological remodeling are called for to improve the post-MI survival rate.…”

mentioning

confidence: 99%

FSTL1 as a Potential Mediator of Exercise-Induced Cardioprotection in Post-Myocardial Infarction Rats

Gong

Tian

2016

Sci Rep

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Exercise training has been reported to ameliorate heart dysfunction in both humans and animals after myocardial infarction (MI), but the underlying mechanisms are poorly understood. Follistatin-like1 (FSTL1) is a cardioprotective factor against ischemic injury and is induced in cardiomyocytes and skeletal muscle in ischemic and hypoxic conditions. To test the hypothesis that FSTL1 may be a molecular link between exercise and improved heart function post MI, we subjected MI-rats, induced by left coronary artery ligation, to two modes of exercise: intermittent aerobic exercise (IAE) or mechanical vibration training (MVT), for four weeks and examined the relevance of FSTL1 to exercise-mediated cardiac effects. Exercise improved the functional performance, reduced fibrosis of MI-hearts and induced FSTL1 expression, the TGFβ-Smad2/3 signaling and angiogenesis in myocardium. In gastrocnemius, exercise increased the cross-sectional area of myocytes and FSTL1 expression. Importantly, exercise increased circulating FSTL1 levels, which were positively correlated with the skeletal muscle FSTL1 expression and negatively correlated with heart fibrosis. Overall, the IAE was more effective than that of MVT in cardioprotection. Finally, exogenous FSTL1 administration directly improved angiogenesis as well as functionality of post-MI hearts. Taken together, we have demonstrated that FSTL1 is a potential mediator of exercise-induced cardioprotection in post-MI rats.

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“…Depression following myocardial infarction or cardiovascular procedures appears to contribute to future cardiovascular events [35]. Fatty acids are key components of normal brain function and omega-3 fatty acids may be important in this regard.…”

Section: Psychiatric and Depressive Disordersmentioning

confidence: 99%

Omega-3 Fatty Acid Blood Levels Clinical Significance Update

Superko

Superko²,

Lundberg

et al. 2014

Curr Cardiovasc Risk Rep

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The potential benefit of fish oil (omega-3 fatty acids) consumption to reduce cardiovascular disease (CVD) risk remains controversial. Some investigations report reduced CVD risk associated with fish or fish oil consumption while others report no benefit. This controversy is in part resolved when consideration is given to omega-3 blood levels in relation to CVD risk as well as blood levels achieved in clinical trials of omega-3 supplementation and CVD benefit. There is a wide variation in omega-3 blood levels achieved between individuals in response to a given dose of an omega-3 supplement. Many studies tested a daily dose of 1 gram omega-3 supplementation. The individual variation in blood omega-3 levels achieved in response to a fixed daily dose helps to explain why some individuals may obtain CVD protection benefit while others do not due to failure to achieve a therapeutic threshold. Recent development of a population range in a United States population helps to provide clinical guidance since population omega-3 blood level ranges may vary due to environmental and genetic reasons. Omega-3 supplementation may also be of benefit in reducing the adverse impact of air pollution on CVD risk.

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Levels of anxiety and depression as predictors of mortality following myocardial infarction: A 5-year follow-up

Cited by 28 publications

References 38 publications

The level of emotion control, anxiety, and self-efficacy in the elderly in Bialystok, Poland

The level of emotion control, anxiety, and self-efficacy in the elderly in Bialystok, Poland

FSTL1 as a Potential Mediator of Exercise-Induced Cardioprotection in Post-Myocardial Infarction Rats

Omega-3 Fatty Acid Blood Levels Clinical Significance Update

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