Leveraging DNA-Based Nanostructures for Advanced Error Detection and Correction in Data Communication

Gao, Ruru; Wei, Xiu-Shen; Chen, Zelin; Xie, Aming; Dong, Wei

doi:10.1021/acsnano.3c04777

Cited by 4 publications

(3 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Molecular logic is an interdisciplinary research field that has attracted worldwide attention. − The most common cases of molecular logic gates include chemical input signals and optical output fluorescent signals. − The logic output can be observed by variation of the emitted fluorescence intensity, and the basis of the logic operation is established by the known Boolean arithmetic function. Clearly, multicolor-based fluorescent ink logic gates offer a new detection strategy in the field of molecular diagnostics. ,− …”

Section: Introductionmentioning

confidence: 99%

Multicolor Fluorescent Inks Based on Lanthanide Hybrid Organogels for Anticounterfeiting and Logic Circuit Design

Lian,

Chang,

Huang

et al. 2024

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

With the rapid development of information technology, the encrypted storage of information is becoming increasingly important for human life. The luminescent materials with a color-changed response under physical or chemical stimuli are crucial for information coding and anticounterfeiting. However, traditional fluorescent materials usually face problems such as a lack of tunable fluorescence, insufficient surface-adaptive adhesion, and strict synthesis conditions, hindering their practical applications. Herein, a series of luminescent lanthanide hybrid organogels (Ln-MOGs) were rapidly synthesized using a simple method at room temperature through the coordination between lanthanide ions and 2,6-pyridinedicarboxylic acid and 5-aminoisophthalic acid. And the multicolor fluorescent inks were also prepared based on the Ln-MOG and hyaluronic acid, with the advantages of being easy to write, coloradjustable, and water-responsive discoloration, which has been applied to paper-based anticounterfeiting technology. Inspired by the responsiveness of the fluorescent inks to water, we designed a logic system that can realize single-input logic operations (NOT and PASS1) and double-input logic operations (NAND, AND, OR, NOR, XOR). The encryption of a binary code can be actualized utilizing different luminescent response modes based on the logic circuit system. By adjusting the energy sensitization and luminescence mechanism of lanthanide ions in the gel structure, the information reading and writing ability of the fluorescent inks were verified, which has great potential in the field of multicolor pattern anticounterfeiting and information encryption.

show abstract

Section: Introductionmentioning

confidence: 99%

Multicolor Fluorescent Inks Based on Lanthanide Hybrid Organogels for Anticounterfeiting and Logic Circuit Design

Lian,

Chang,

Huang

et al. 2024

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

show abstract

“…The distinction between true and false signals is achieved through thresholds . Over the past several decades, biomolecular logic gates have garnered significant attention for their ability to emulate conventional microprocessors at the molecular level, executing Boolean logic computations based on binary principles. − This facilitates functions such as error detection, − information processing, − and data storage. , Among them, DNA has emerged as a promising candidate for constructing logic gates and circuits in biocomputing due to its programmability, high specificity, and addressability. − Several groups promote the development in information processing by constructing the logic circuit, analogue circuit, combinational circuit, and information relay with DNA nanostructures. Data transmission can be hindered by noise or interference.…”

mentioning

confidence: 99%

“…However, it is unable to determine the error location and correct it using a parity check. To meet this challenge, Wei et al have employed DNA-based nanostructures to implement the Hamming code for error detection and correction in communication . In addition to error detection and correction, biomolecular logic gates have been applied in information steganography and authentication to improve the security of transmitted data.…”

mentioning

confidence: 99%

DNA Molecular Computation Using the CRISPR-Mediated Reaction and Surface Growth of Gold Nanoparticles

Fu,

Hou,

Wang

et al. 2024

ACS Nano

View full text Add to dashboard Cite

DNA has emerged as a promising tool to build logic gates for biocomputing. However, prevailing methodologies predominantly rely on hybridization reactions or structural alterations to construct DNA logic gates, which are limited in simplicity and diversity. Herein, we developed simple and smart DNA-based logic gates for biocomputing through the DNA-mediated growth of gold nanomaterials without precise structure design and probe modification. Capitalizing on their excellent plasmonic properties, the surface growth of gold nanomaterials enables distinct wavelength shifts and unique shapes, which are modulated by the composition, length, and concentration of the DNA sequences. Combined with a CRISPR-mediated reaction, we constructed DNA circuits to achieve complicated biocomputing to modulate the surface growth of gold nanomaterials. By implementing logic functions controlled by input-mediated growth of gold nanomaterials, we established YES/NOT, AND/NAND, OR/NOR, XOR, and INHIBIT gates and further constructed cascade logic circuits, parity checker for natural numbers, and gray code encoder, which are promising for DNA biocomputing.

show abstract

Dynamic Time-Programming Circuit for Encoding Information, Programming Dissipative Systems, and Delaying Release of Cargo

Wang,

Luo

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

Living systems have some of the most sophisticated reaction circuits in the world, realizing many incredibly complex functions through a variety of simple molecular reactions, in which the most notable feature that distinguishes them from artificial molecular reaction networks is the precise control of reaction times and programmable expression. Here, we exploit the hydrolysis-directed nature of λ exonuclease and the programmed responses of the dynamic nanotechnology of nucleic acids to construct a simple, complete, and powerful set of temporally programmed circuits. This system can arbitrarily regulate the degradation rate of the blocker, thereby delaying the nucleic acid chain substitution reaction with less signal leakage. In addition, the powerful dynamic reaction network of nucleic acids enabled us to control the programmed execution of a wide range of reactions in different fields. We have developed a simple strategy to introduce precise control of the time dimension into nucleic acid reaction circuits, which greatly enriches the functionality and applicability of the reaction programs, which can be easily used as timers, compilers, converters, etc. The simplicity, precision, stability, and versatility of such dynamic temporal programming circuits greatly expand the potential of artificial molecular reaction networks for more complex practical applications in biochemistry and molecular biology.

show abstract

Leveraging DNA-Based Nanostructures for Advanced Error Detection and Correction in Data Communication

Cited by 4 publications

References 38 publications

Multicolor Fluorescent Inks Based on Lanthanide Hybrid Organogels for Anticounterfeiting and Logic Circuit Design

Multicolor Fluorescent Inks Based on Lanthanide Hybrid Organogels for Anticounterfeiting and Logic Circuit Design

DNA Molecular Computation Using the CRISPR-Mediated Reaction and Surface Growth of Gold Nanoparticles

Dynamic Time-Programming Circuit for Encoding Information, Programming Dissipative Systems, and Delaying Release of Cargo

Contact Info

Product

Resources

About