Levonorgestrel-releasing Intrauterine Device is an Efficacious Contraceptive for Women with Leiomyoma

Role of levonorgestrel releasing intra-uterine system in the treatment of menorrhagia due to dysfunctional uterine bleeding and fibroid uterus

“…In a study of 30 fibroid patients receiving LNG-IUS with the primary aim of contraception, no pregnancy was reported during the 12 months follow-up period. 21 Significant reduction in blood loss and improvement in haemoglobin levels was reported in their study, and there was only one expulsion. There were however, no changes in both uterine as well as myoma volumes.…”

Levonorgestrel-releasing intrauterine device use as an alternative to surgical therapy for uterine leiomyoma

“…Therefore, lack of long-term follow up (> one year) is a recognized limitation of the present study, which otherwise might be beneficial in terms of a more accurate assessment of volumetric alterations related to insertion of LNG-IUS. However, it is proposed that three months follow up might be sufficient to observe a reduction in the incidence of bleeding disturbances [19].…”

Long-Acting Reversible Contraception

“…25 Regarding leiomyoma, a systematic review evaluated eight studies that reported on hormonal IUD expulsion rates among women with uterine leiomyomas and concluded that expulsion rates may be higher in this group, although no comparative studies achieved a statistically significant difference in expulsion rates between women with leiomyomas and those without leiomyomas. 26 Given the limited data, IUDs cannot be recommended for patients with uterine cavity distortion seeking contraception. Intrauterine devices may be considered for those seeking only noncontraceptive IUD benefits who are willing to accept the possible increased risk of expulsion or other complications.…”