2011
DOI: 10.1089/jpm.2011.9673
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Levorphanol #240

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“… 18 There is no cytochrome P450 system involvement in this process, limiting drug–drug interaction. 19 …”
Section: Levorphanol: Pharmacologic Characteristicsmentioning
confidence: 99%
“… 18 There is no cytochrome P450 system involvement in this process, limiting drug–drug interaction. 19 …”
Section: Levorphanol: Pharmacologic Characteristicsmentioning
confidence: 99%
“…Its long halflife (11-16 hours) means baseline doses should not be increased before steady state is reached (2-3 days). Table 3 shows the equianalgesic ratio of levorphanol (and methadone) to morphine varies by dose (Loitman, 2011). Phase 2 metabolism results in inactive metabolites excreted in urine.…”
Section: Levorphanol (Po)mentioning
confidence: 99%