Lhermitte-Duclos Disease in a Six-Year Old Child: A Rare Presentation

Abstract

Lhermitte-Duclos disease (LDD) is a rare, slow-growing, benign lesion of the cerebellum. It is often seen in the second and fourth decades. This disease is extremely rare in childhood. A 6-year-old girl presented with loss of balance. A mass lesion in the right cerebellum was detected by magnetic resonance imaging. The patient underwent surgical removal of the lesion, and the histological diagnosis was dysplastic gangliocytoma (LDD). The patient was discharged without complication, and her balance improved in the follow-up period. In this report, we present this rare occurrence in childhood and discuss the clinical course and management. LDD is very rare in early childhood and should be considered in the differential diagnosis of posterior fossa lesions.

Lhermitte-Duclos Disease in Pediatric Population: Report of 2 Cases

“…The thickened folia loses its architecture, making the cerebellar hemisphere to expand asymmetrically [22]. Some case reports are found in the literature, predominantly in young and adult patients, whereas it is a very rare disease in childhood [19].…”

“…Few cases of pediatric LDD and LDD-associated Cowden syndrome have been reported previously in the literature [13][14][15][16][17][18][19]. The aim of this study was to describe clinical symptoms and radiological and histopathological features of LDD and analyze the relation to Cowden syndrome in pediatric population.…”

Dysplastic cerebellar gangliocytoma: a description of two cases

“…DCG usually presents in the third and fourth decades of life and rarely in children (2)(3)(4), with no gender or race preponderance. Size of lesion, laterality, and disease duration vary considerably (5).…”

A Case Report of Lhermitte-Duclos Disease in a 10-Month-Old Child Presenting with Hydrocephalus

“…The natural history of LDD is not well known 9 . Defi nitive treatment of LDD is very controversial.…”