Li+ in Bipolar Disorder – Possible Mechanisms of Its Pharmacological Mode of Action

Fonseca, Carla P.; Castro, M. Margarida C. A.

doi:10.5772/34560

Bipolar Disorder - A Portrait of a Complex Mood Disorder 2012

DOI: 10.5772/34560

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Li+ in Bipolar Disorder – Possible Mechanisms of Its Pharmacological Mode of Action

Carla P. Fonseca¹,

M. Margarida C. A. Castro²

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2014

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Cited by 1 publication

References 102 publications

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Pharmacokinetics of Lithium in Egyptian Bipolar Patients: Dosage Adjustment Approach

Ebid¹,

Abd-Allah²,

Elhabiby³

2014

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Due to its proven clinical effectiveness, lithium has been considered as a corner stone for the long-term treatment of Bipolar Disorder (BPD) for more than half a century. The objective of this study was to evaluate the effect of patients' different co-variables on lithium pharmacokinetics and the development of a pharmacokinetic model for the estimation of lithium clearance in Egyptian bipolar patients; this model can be used afterwards during dosage adjustment to achieve target's steady-state plasma concentrations in similar settings. The study was conducted on 65 adult Egyptian bipolar patients of both genders, in both the in-and outpatient settings in the

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Pharmacokinetics of Lithium in Egyptian Bipolar Patients: Dosage Adjustment Approach

Ebid¹,

Abd-Allah²,

Elhabiby³

2014

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Li+ in Bipolar Disorder – Possible Mechanisms of Its Pharmacological Mode of Action

Cited by 1 publication

References 102 publications

Pharmacokinetics of Lithium in Egyptian Bipolar Patients: Dosage Adjustment Approach

Pharmacokinetics of Lithium in Egyptian Bipolar Patients: Dosage Adjustment Approach

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