2024
DOI: 10.1038/s41556-024-01469-w
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LIANA+ provides an all-in-one framework for cell–cell communication inference

Daniel Dimitrov,
Philipp Sven Lars Schäfer,
Elias Farr
et al.

Abstract: The growing availability of single-cell and spatially resolved transcriptomics has led to the development of many approaches to infer cell–cell communication, each capturing only a partial view of the complex landscape of intercellular signalling. Here we present LIANA+, a scalable framework built around a rich knowledge base to decode coordinated inter- and intracellular signalling events from single- and multi-condition datasets in both single-cell and spatially resolved data. By extending and unifying estab… Show more

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Cited by 7 publications
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