Lichen Myxedematosus

Howsden, Susan M.

doi:10.1001/archderm.1975.01630220089007

Cited by 52 publications

(2 citation statements)

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“…Melphelan produced no long lasting benefit in our patient as it did in the case of Feldman et al (1969). There has been a report by Howsden, Herndon & Freeman (1975) ofa dramatic response of lichen myxoedematosus to the use of cyclophosphamide and it is hoped to start our patient on this treatment.…”

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confidence: 50%

(24) Lichen myxoedematosus

Byrne

Marten

2006

British Journal of Dermatology

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confidence: 50%

(24) Lichen myxoedematosus

Byrne

Marten

2006

British Journal of Dermatology

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“…As for other immunological examinations, Fowlkes et al (16) reported that his case was normal with regard to delayed type reaction and humoral antibody production. It has been reported that autoantibodies such as RA factor, antinuclear antibody, LE factor are frequently negative (4,7,8,10,12,(17)(18)(19) but are positive in some instances, Howsden et al (9) reported a case not associated with paraprotein, in which the immunofluorescence examination was positive and the antinuclear antibody became transiently positive and this case, responded well to cyclophosphamide. There is also a case associated with chronic rheumatism of the joints but no detailed analysis of this case was done (20).…”

Section: Case Reportmentioning

confidence: 69%

A Case of Lichen Myxedematosus Associated With Immunological Abnormalities

Akiyama

Hori

Yamaura

et al. 1977

The Journal of Dermatology

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A 33-year-old male consulted us with symptoms of band-like infiltration, thickenning and subcutaneous induration occurring in the face, chest, back, shoulder and upper extremities. In the following time he developed arthralgia, fever and ocular symptoms. Laboratory tests revealed normal thyroid functions and a normal bone marrow picture, but there were immunological abnormalities such as reduced cellular immunity, decrease in C 3 (beta 1c/la) and positive antinuclear antibody. Histologically, there was an increase in fibroblasts and deposits of hyaluronic acid were revealed histochemically. A diagnosis of lichen myxedematosus was established. At present, all symptoms and signs including skin rash have disappeared following corticosteroid therapy and the patient is being followed up. So far as we have been able to trace, reports on lichen myxedematosus associated with immunological abnormalities as described here have not been found. The relationship between this pathology and immunological abnormalities are discussed.

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The Cutaneous Plasma Cell Dyscrasias

Nir

Osserman

1981

Immunodermatology

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Lichen Myxedematosus

Cited by 52 publications

References 0 publications

(24) Lichen myxoedematosus

(24) Lichen myxoedematosus

A Case of Lichen Myxedematosus Associated With Immunological Abnormalities

The Cutaneous Plasma Cell Dyscrasias

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