Lichen planus pigmentosus inversus: a series of 10 Tunisian patients

Mohamed, M.; Korbi, M.; Hammedi, Faten; Youssef, M.; Soua, Y.; Akkari, H.; Lahouel, Ines; Belhadjali, H.; Zili, Jameleddine

doi:10.1111/ijd.13295

Cited by 25 publications

(36 citation statements)

References 10 publications

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“…It predominantly affects women, mostly after 40 years, but has been described in individuals 15–82 years of age. LPP‐inversus affects fair and dark skin, with a worldwide distribution . Its pathogenesis is similar to LPP, but in LPP‐inversus a transition from papular LP to macular lesions of LPP has been observed.…”

Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

“…Hepatitis C virus has also been associated with LPP‐inversus . Hormonal factors could be involved as it occurs in patients with frontal fibrosing alopecia, which tends to occur in women during perimenopause and postmenopause …”

Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

“…LPP‐inversus affects flexural areas, mainly the axillae, groin, submammary folds, and antecubital and popliteal fossae; however, the inner wrist, gluteal cleft, auricular sulci, abdominal folds, lumbar back, and neck can also be involved . It is characterized by dark brown to violaceous‐gray oval or linear macules with longitudinal axis along the lines of cleavage (Fig.…”

Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

“…Triggers (friction and wearing of tight clothing) must be avoided . Spontaneous resolution of lesions has been reported …”

Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

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Lichen planus pigmentosus and its variants: review and update

Robles-Méndez¹,

Rizo-Frías²,

et al. 2017

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Lichen planus pigmentosus (LPP) is considered a rare variant of lichen planus (LP). It is characterized by acquired dark brown to gray macular pigmentation located on sun-exposed areas of the face, neck, and flexures, commonly found in dark-skinned patients. In patients with LPP, an inflammatory lichenoid response results in marked pigmentary incontinence. It has been associated with hepatitis C virus, sun exposure, and contactants such as mustard oil and nickel. LPP-inversus affects fair and dark skin, predominantly involving flexural and intertriginous areas, while sun-exposed areas are spared; friction is an associated trigger. LPP along Blaschko's lines has been associated with susceptibility to genetic mosaicisms. LPP can present concomitantly with other variants of LP such as frontal fibrosing alopecia, as well as endocrinopathies, and autoimmune diseases. Treatment is difficult and consists of avoidance of triggers and topical and systemic medications in order to stop the inflammatory reaction and reduce pigmentation, improving aesthetic appearance and quality of life.

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Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

“…Triggers (friction and wearing of tight clothing) must be avoided . Spontaneous resolution of lesions has been reported …”

Section: Lichen Planus Pigmentosus Inversus (Lpp‐inversus)mentioning

confidence: 99%

See 2 more Smart Citations

Lichen planus pigmentosus and its variants: review and update

Robles-Méndez¹,

Rizo-Frías²,

et al. 2017

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“…In Indians, specifically, mustard oil containing the photosensitizing agent allyl thiocyanate is postulated to contribute to disease development given its ubiquity and multifaceted use in Indian culture . Lichen planus pigmentosus‐inversus is yet another rare variant of the disease that is more common among Caucasians and Asians but has also been reported among North Africans with dark skin phototypes . This manifests as symmetric dark brown macules primarily in the intertriginous areas, most commonly the axillae.…”

Section: Photoaggravated Dermatosesmentioning

confidence: 99%

Photodermatoses in skin of colour

Gutiérrez

Gaulding

Beltran

et al. 2018

Acad Dermatol Venereol

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Photodermatoses represent a heterogeneous collection of disorders unified by the characteristic of being provoked through exposure to ultraviolet radiation. Generally, these conditions are classified into the following categories: immunologically mediated photodermatoses, chemical- and drug-induced photosensitivity, photoaggravated dermatoses and photosensitivity associated with defective DNA repair mechanisms or chromosomal instabilities. The list of photodermatoses is extensive, and each individual photodermatosis is understood to a different extent. Regardless, there exists a paucity of information with regards to the clinical presentation among those with skin of colour. With ever-changing global demographics, recognition of photosensitive disorders in a diverse population is essential for accurate diagnoses and therapeutic guidance. The scope of this article seeks to review the epidemiology and clinical variability in presentation of such photodermatoses in patients with skin of colour.

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