Lichen planus with bullous manifestation on the lip

Serooskerken, Anne-Moon van Tuyll van; Marion, Ariënne M W van; Zwart-Storm, Eugene de; Frank, Jorge; Poblete‐Gutiérrez, Pamela

doi:10.1111/j.1365-4632.2007.03506.x

Cited by 21 publications

(17 citation statements)

References 9 publications

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“…Es una erupción pápulo-escamosa que puede comprometer la piel, el cuero cabelludo, las uñas y las mucosas (2,4). El término liquen plano fue introducido por primera vez en 1869 por Erasmus Wilson, para nombrar una condición que había sido descrita por Hebra como "leichenruber" (2). Viene del griego leichen que significa musgo y del latín planus que significa aplanado (3).…”

Section: Discussionunclassified

Liquen plano ampolloso en la edad pediátrica, una adecuada respuesta al tratamiento con esteroide oral

2014

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ResumenEl liquen plano es una erupción pápulo-escamosa de la cual se han descrito numerosas variantes en su presentación clínica. Una de esas variantes es el liquen plano ampolloso, en la que se desarrollan vesículas y ampollas que se originan de las pápulas características del liquen plano, o rara vez, de piel de aspecto normal. Debido a la formación de ampollas, el diagnóstico diferencial incluye liquen plano penfigoide, penfigoide ampolloso, pénfigo vulgar, eritema multiforme e infección por virus del herpes, por lo tanto, el examen histopatológico es útil para el diagnóstico definitivo. Las opciones de tratamiento incluyen esteroides tópicos y sistémicos, retinoides sistémicos, fototerapia, antimaláricos y agentes inmunosupresores. Se presenta el caso de una niña con diagnóstico clínico de liquen plano ampolloso que fue confirmado por histopatología, destacando la importancia de conocer esta rara variante y demostrando la adecuada respuesta al tratamiento con esteroides orales.Palabras clave: Liquen plano, ampollas, esteroides. BULLOUS LICHEN PLANUS IN CHILDREN, AN ADEQUATE RESPONSE TO TREATMENT WITH ORAL STEROID AbstracLichen planus is a papulosquamous eruption whith numerous clinical variants. One of these variants is bullous lichen planus in which vesicles and blisters develop originating from lichen planus papules, or rarely in normal-looking skin. Due to formation of blisters, differential diagnosis includes lichen planuspemphigoid, bullous pemphigoid, pemphigus vulgaris, erythema multiforme and herpes virus infection, therefore histopathological examination is essential for a definitive diagnosis. Teatment includes topical and systemic steroids, systemic retinoids, phototherapy, antimalarials and immunosuppressive agents. We report the case of a child with clinical diagnosis of bullous lichen planus confirmed by histopathology,emphazise the importance of this rare variant and demonstrating the adequate response to treatment with oral steroid.

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Section: Discussionunclassified

Liquen plano ampolloso en la edad pediátrica, una adecuada respuesta al tratamiento con esteroide oral

2014

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“…Mucosal labial lesions may occur, but buccal mucosal, tongue, and gums are more commonly affected. Bullous LP is exceedingly rare on the lips [7]. At times, very severe and chronic forms of erosive LP can lead to atrophy and scarring, mainly on mucosal sites.…”

Section: Clinical Aspectsmentioning

confidence: 99%

“…Potent topical corticosteroids are the first line therapy. Clobetasol propionate, betamethasone, or triamcinolone, are more commonly used [5,7,11]. A good approach is to decrease steroid potency as lesions improve.…”

Section: Treatmentmentioning

confidence: 99%

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Lichen Planus Affecting the Lips

Fern¹,

es²,

Lourenço³

2015

Clin Exp Dermatol Res

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Lichen planus frequently compromises the skin, and the oral mucosa. There is plenty of medical and dental literature about the cutaneous and mucosal lesions of lichen planus, but, comparatively very little has been written specifically about lichen planus compromising the lip vermilion. This structure has a peculiar anatomical and histological architecture, and lichen planus lesions at this site may have some distinct features. This article reviews the recent literature about labial lichen planus in all of its presentations, highlighting some special clinical features that may enable a better diagnosis and differential diagnosis of lip diseases. Besides, personal experience by the authors is added.

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“…33 Topical application of tretinoin 0.025% in combination with triamcinolone 0.1% has also been used successfully for treating lichen planus with bullous manifestation on the lip. 34 Antimalarial drugs have been indicated as a possible treatment option. 35 Recently, we described the first case of BLP treated successfully with acitretin monotherapy.…”

Section: Treatmentmentioning

confidence: 99%

Bullous lichen planus – a review

Liakopoulou¹,

Rallis²

2017

J Dermatol Case Rep

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Bullous lichen planus is a rare variant of lichen planus. It is characterized by vesicles or bullae, which usually develop in the context of pre-existing LP lesions. It is often misdiagnosed and should be differentiated from other subepidermal bullous diseases especially lichen planus pemphigoides. The diagnosis is based on clinical suspicion and is confirmed by histopathology and immunofluoresence. The clinical features of bullous lichen planus include typical lichen planus lesions, accompanied by the formation of bullae on the affected or perilesional skin. This is evident on histology, with alteration of the dermo-epidermal junction and intrabasal bullae as a consequence of extensive inflammation. The histologic features in conjunction with the negative immunofluoresence indicate that bullous lichen planus is a form of "hyper-reactive lichen planus" rather than a distinct entity. There is no standard treatment of bullous lichen planus. Topical and systemic corticosteroids, dapsone and acitretin have been described as effective choices.

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Lichen planus with bullous manifestation on the lip

Cited by 21 publications

References 9 publications

Liquen plano ampolloso en la edad pediátrica, una adecuada respuesta al tratamiento con esteroide oral

Liquen plano ampolloso en la edad pediátrica, una adecuada respuesta al tratamiento con esteroide oral

Lichen Planus Affecting the Lips

Bullous lichen planus – a review

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