Lichen sclerosus-lichen planus overlap in a patient with hepatitis C virus infection

Abstract

Influence of environmental temperature on the occurrence of non-necrotizing cellulitis of the leg SIR, Non-necrotizing cellulitis of the leg is a common cutaneous bacterial infection whose risk factors include venous insufficiency, lymphoedema and toe-web intertrigo. The role of environmental temperature remains controversial. 1 To study the relationship between environmental temperature and the frequency of non-necrotizing cellulitis of the leg, we reviewed all patients hospitalized with nonnecrotizing cellulitis of the leg in a university hospital in a temperate region of France during a 4-year period, and correlated findings with the local environmental temperature during the same period.Patients included in this study were consecutive patients referred for non-necrotizing cellulitis of the leg from January 1995 to December 1998 in the Departments of Dermatology, Internal Medicine and Infectious Diseases of the Rouen University Hospital. The diagnosis of cellulitis of the leg was retrospectively identified using the database of the Medical Information System. The mean and maximum temperatures of each the 8 days prior to the date of hospital admission were obtained from the local meteorological unit for each case. Correlations between the mean and maximum daily temperature of each day from day ) 8 to the admission day (lag 0-8 days) and the daily number of patients hospitalized for cellulitis of the leg were studied using a nonparametric Poisson regression model to adjust for time trends and days of the week (generalized additive model). 2 Eight hundred and ninety-eight patients with cellulitis of the leg [342 men (38%) and 556 women (62%)] were

Unexpectedly High Frequency of Genital Involvement in Women with Clinical and Histological Features of Oral Lichen Planus

“…Regarding overlapping syndrome VLP/VLS, some authors (8,32,33) have suggested that these two aspects may represent a transitional stage to a unique disease rather than the coexistence of two distinct entities (8). In our opinion, differential diagnosis between VLP and VLS is difficult, particularly in the late stage of disease when fibrosis aspects, typical of VLS.…”

Lichen sclerosus of lips: a clinical and histopathologic study of 27 cases

“…6a,b). However, presence of lichenoid infiltrates in early genital LS has been acknowledged by many investigators, 4,5,23–28 and it is possible that lichenoid interface dermatitis is a fore runner in the pathogenesis of LS, which may later evolve into vacuolar interface dermatitis. Linear studies with repeated histologic examinations are needed to prove this point.…”

Evidence‐based (S3) Guideline on (anogenital) Lichen sclerosus

“…Borrelia burgdorferi or a human papilloma virus, has been postulated but there are no clear data showing that LS is related to an infection (Lau ; Nasca 2006; Nieuwenhof HP van ; Gambichler ; Edmonds ; Alonso‐Llamazares ). There are sporadic reports of LS associated with a hepatitis C infection (Shim ; Yashar ; Boulinguez ).…”