LiClO₄‐Activated Stereo‐ and Regioselective Alkylation of Aldehydes.

Abstract

An effective, mild and stereoselective alkylation of aldehydes with tertiary alcohols or alcoholates in the presence of LiClO4 and acid is described. This new methodology enables the inclusion of a broad range of aldehydes as well as tertiary alcohols. -(MARKERT, M.; BUCHEM, I.; KRUEGER, H.; MAHRWALD*, R.; Tetrahedron 60 (2004) 4, 993-999; Inst. Chem.,