Lidocaine patches for postcesarean pain control in obese women: a pilot randomized controlled trial

Antony, Kathleen M.; Adams, Jacquelyn H.; Jacques, L; Hetzel, Scott; Chappell, Richard J.; Gnadt, Sarah E.; Tevaarwerk, Amye J.

doi:10.1016/j.ajogmf.2020.100281

Cited by 8 publications

(9 citation statements)

References 68 publications

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“…The majority included implementation of multimodal stepwise protocols (n = 8) 16–23 or changes in dosages or timing of medication administration (n = 4) 24–27 . Four additional studies included interventions that compared nonopioid medication with placebo, 28 use of lidocaine patches, 29 abdominal binder, 30 and battlefield acupuncture, in which needles are placed only on the surface of the ear (Table 1). 31 …”

Section: Resultsmentioning

confidence: 99%

“…The majority included implementation of multimodal stepwise protocols (n = 8) [16][17][18][19][20][21][22][23] or changes in dosages or timing of medication administration (n = 4). [24][25][26][27] Four additional studies included interventions that compared nonopioid medication with placebo, 28 use of lidocaine patches, 29 abdominal binder, 30 and battlefield acupuncture, in which needles are placed only on the surface of the ear (Table 1 ). 31 The 8 studies that evaluated multimodal stepwise interventions were all retrospective cohort studies [16][17][18][19][20][21][22][23] and included initiating scheduled ibuprofen and acetaminophen, with the administration of an opioid on an as-needed basis for breakthrough pain.…”

Section: Interventions To Reduce Postpartum Opioid Use During the Inp...mentioning

confidence: 99%

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Interventions to Reduce Inpatient and Discharge Opioid Prescribing for Postpartum Patients: A Systematic Review

Badreldin

DiTosto

Holder

et al. 2023

J Midwife Womens Health

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Introduction As deaths related to opioids continue to rise, reducing opioid use for postpartum pain management is an important priority. Thus, we conducted a systematic review of postpartum interventions aimed at reducing opioid use following birth. Methods From database inception through September 1, 2021, we conducted a systematic search in Embase, MEDLINE, Cochrane Library, and Scopus including the following Medical Subject Heading (MeSH) terms: postpartum, pain management, opioid prescribing. Studies published in English, restricted to the United States, and evaluating interventions initiated following birth with outcomes including an assessment of change in opioid prescribing or use during the postpartum period (<8 weeks postpartum) were included. Authors independently screened abstracts and full articles for inclusion, extracted data, and assessed study quality using the Grading of Recommendations, Assessment, Development, and Evaluation tool and risk of bias using the Institutes of Health Quality Assessment Tools. Results A total of 24 studies met inclusion criteria. Sixteen studies evaluated interventions aimed at reducing postpartum opioid use during the inpatient hospitalization, and 10 studies evaluated interventions aimed at reducing opioid prescribing at postpartum discharge. Inpatient interventions included changes to standard order sets and protocols for the management of pain after cesarean birth. Such interventions resulted in significant decreases in inpatient postpartum opioid use in all but one study. Additional inpatient interventions, including use of lidocaine patches, postoperative abdominal binder, valdecoxib, and acupuncture were not found to be effective in reducing postpartum opioid use during inpatient hospitalization. Interventions targeting the postpartum period included individualized prescribing and state legislative changes limiting the duration of opioid prescribing for acute pain both resulted in decreased opioid prescribing or opioid use. Discussion A variety of interventions aimed at reducing opioid use following birth have shown efficacy. Although it is not known if any single intervention is most effective, these data suggest that implementation of any number of interventions may be advantageous in reducing postpartum opioid use.

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Section: Resultsmentioning

confidence: 99%

Section: Interventions To Reduce Postpartum Opioid Use During the Inp...mentioning

confidence: 99%

Interventions to Reduce Inpatient and Discharge Opioid Prescribing for Postpartum Patients: A Systematic Review

Badreldin

DiTosto

Holder

et al. 2023

J Midwife Womens Health

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“…A total of 140 studies (PubMed 43, Cochran 71, and Embase 26) were retrieved. After screening, 16 randomized controlled trials (RCTs) were included 12–14,16–28 . The data from 918 patients were obtained, of which 462 patients used lidocaine patches, and 456 patients did not use patches or used blank patches.…”

Section: Resultsmentioning

confidence: 99%

“…Five trials provided data on patient satisfaction 16–20 . The lidocaine patch groups seemed to have a higher patient satisfaction, but the difference was not significant (risk ratio, 1.50 [95% CI, 0.74 to 3.05], P =0.26) (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…After screening, 16 randomized controlled trials (RCTs) were included. [12][13][14][16][17][18][19][20][21][22][23][24][25][26][27][28] The data from 918 patients were obtained, of which 462 patients used lidocaine patches, and 456 patients did not use patches or used blank patches. The characteristics of the included trials are shown in Table 2.…”

Section: Resultsmentioning

confidence: 99%

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Is Lidocaine Patch Beneficial for Postoperative Pain?

Wu¹,

Wei

et al. 2023

The Clinical Journal of Pain

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Objectives: The aim of this meta-analysis was to evaluate whether a lidocaine patch is beneficial for postoperative pain as an option for multimodal analgesia. Methods: Information was obtained from PubMed, Embase, and the Cochrane Central Register of Controlled Trials for clinical randomized controlled trials of lidocaine patches for postoperative pain (as of March 2022). Two researchers independently completed study screening, risk bias assessment, and data extraction. Review Manager (version 5.4, Cochrane Collaboration) was used to conduct the meta-analysis. The evaluation metrics were postoperative pain scores, opioid consumption, and patient satisfaction. Results: Sixteen randomized controlled trials were included, and data from 918 patients were available. Pain scores differed between the 2 groups at 12, 24, and 48 hours postoperatively, and the pain scores of the lidocaine patch group were significantly lower (mean difference [MD]=−1.32 [95% CI, −1.96 to −0.68], P<0.0001; I 2=92%) at 12 hours after the operation; (MD=−1.23 [95% CI, −1.72 to −0.75], P<0.00001; I 2=92%) at 24 hours after the operation; and (MD=−0.25 [95% CI,−0.29 to −0.21], P<0.00001; I 2=98%) at 48 hours after the operation. In addition, the lidocaine patch group had decreased opioid requirements (MD=−3.57 [95% CI, −5.06 to −2.09], P<0.00001; I 2=96%). The lidocaine patch group seemed to be more satisfied, but there was no statistically significant difference (risk ratio, 1.50 [95% CI, 0.74 to 3.05], P=0.26) between the groups. Discussion: Lidocaine patches are beneficial for postoperative pain and can be used in multimodal analgesia to reduce opioid use, but there is no significant increase in patient satisfaction with pain control. More data are needed to support this conclusion due to the large heterogeneity in the present study.

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Surgical transversus abdominis plane block with liposomal bupivacaine at cesarean: a pilot randomized trial

Antony,

McDonald,

Gaston

et al. 2024

American Journal of Obstetrics & Gynecology MFM

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Lidocaine patches for postcesarean pain control in obese women: a pilot randomized controlled trial

Cited by 8 publications

References 68 publications

Interventions to Reduce Inpatient and Discharge Opioid Prescribing for Postpartum Patients: A Systematic Review

Interventions to Reduce Inpatient and Discharge Opioid Prescribing for Postpartum Patients: A Systematic Review

Is Lidocaine Patch Beneficial for Postoperative Pain?

Surgical transversus abdominis plane block with liposomal bupivacaine at cesarean: a pilot randomized trial

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