Life Begins at Forty!

Carter, Naomi; O'Driscoll, MarieLuce

doi:10.1016/s0031-9406(05)61210-2

Cited by 4 publications

(2 citation statements)

References 40 publications

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“…Exercise and physical activities are the most important factors in maintaining health. According to studies, exercise can be effective in maintaining and enhancing good feelings, functional ability, and reducing medical problems and economic costs (25). In contrast, immobility and lack of regular physical activity leads to many diseases, including cardiovascular disease, diabetes, cancers, and other risk factors, such as high blood pressure, high blood sugar, overweightness, and obesity.…”

Section: Discussionmentioning

confidence: 99%

Students’ Health Promoting Behaviors: A Case Study at Shiraz University of Medical Sciences

et al. 2018

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Background: One of the most important factors determining the health of individuals is their health promoting behaviors. Objectives: This study was conducted to investigate the status of health promoting behaviors of students at Shiraz University of Medical Sciences. Methods: This cross-sectional descriptive-analytical study was conducted on 370 students of Shiraz University of Medical Sciences, during year 2017. Data were collected through a standard health-promoting lifestyle questionnaire that was designed with 10 dimensions (physical health, exercise and wellbeing, weight and nutrition control, disease prevention, psychological health, spiritual health, social health, refrain from drug, accident prevention and environmental health with a total of 70 questions). Data were analyzed using descriptive statistics, T-test, analysis of variance (ANOVA), and Pearson's correlation coefficient by the SPSS software, version 23, at a significance level of α = 0.05. Results: The mean score of total health promoting behaviors was evaluated as 4.70 ± 1.20, which was in a good range. Avoiding medicines and drugs (5.14 ± 1.08) had the highest and exercise and health (4.07 ± 1.50) had the lowest mean score. There was a positive and significant correlation between all components of health promoting behaviors (P < 0.05). There was a significant differences between demographic variables, such as gender (P = 0.04) and university entrance year (P = 0.00), and total health promoting behaviors. Conclusions:The status of health promoting behaviors was estimated to be desirable. Also, holding health education programs focusing on exercise and health in academic settings is recommended.

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Section: Discussionmentioning

confidence: 99%

Students’ Health Promoting Behaviors: A Case Study at Shiraz University of Medical Sciences

et al. 2018

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“…AAV infects both dividing and non-dividing cells, including neurons or muscle cells and the derived AAV vectors allow integration and sustained expression of transgenes without causing toxicity or immune response. Nevertheless, their small size restricts use to the delivery of small transgenes of up to 5 Kb [76]. The wild-type virus specifically integrates in a particular site in chromosome 19, a property that is lost upon engineering of the vector.…”

Section: Herpes Simplex-derived Vectors 33 Adeno-associated Viral Vmentioning

confidence: 99%

Liposomal and Viral Vectors for Gene Therapy of the Central Nervous System

Lima

Cruz

Cardoso³

et al. 2005

CDTCNSND

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Due to the presence of the blood-brain barrier, the central nervous system (CNS) is not easily accessible to systemically delivered macromolecules with therapeutic activity such as growth factors, cytokines or enzymes. Therefore, the expression of exogenously administered genes in the brain has been proposed for a wide variety of inherited and acquired diseases of the CNS, for which classical pharmacotherapy is unavailable or not easily applicable. Gene therapy to the CNS has been the target of a great number of studies aiming at finding a viable therapeutic strategy for the treatment of neurological disorders. This approach has already been used as a promising tool for brain protection and repair from neuronal insults and degeneration in several animal models, and is currently being applied in clinical trials. The choice of an appropriate vector system for transferring the desired gene into the affected brain area is an important issue for developing a safe and efficient gene therapy approach for the CNS. In this review, we focus on the various types of vectors that have been used for gene delivery into the CNS. Particular emphasis is given to their mode of preparation, biological activity, safety and in vivo behavior. Examples illustrating the potential of both viral and non-viral vectors in therapeutic applications to brain disorders are provided. In addition, the use of lentiviral vectors for in vivo modeling of genetic disorders of the CNS is discussed.

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A study of perceived factors affecting patients' participation in outpatient stroke physiotherapy exercise in Nigeria

Olaleye

Suddick

2012

International Journal of Therapy and Rehabilitation

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Background/Aims: Stroke results in a range of disabilities, activities and restrictions which have been shown to benefit from physiotherapy rehabilitation and exercise. However there are numerous factors that prevent stroke patients from participating in their exercise programmes. The aim of this study was to explore the factors that were perceived to affect people with stroke in Nigeria in participating in their outpatient physiotherapy exercise. Methods: Semi-structured interviews were used to explore the topic. The interviews were transcribed and analyzed using thematic analysis. Eight male participants with stroke who were attending outpatient stroke physiotherapy in Nigeria were recruited in December 2009. Findings: The factors that were perceived to affect the participants' participation in their outpatient physiotherapy programme encompassed three dimensions: the internal and personal, the relational and experiential, and external factors. These dimensions were interconnected with the internal and personal factors being central to the participants' participation. Conclusions: This study has provided an insight into the factors that were important for a small group of Nigerian men post-stroke who were receiving out-patient stroke physiotherapy. This can lead to further research that could assist in informing the development of clinical practice and services.

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Life Begins at Forty!

Cited by 4 publications

References 40 publications

Students’ Health Promoting Behaviors: A Case Study at Shiraz University of Medical Sciences

Students’ Health Promoting Behaviors: A Case Study at Shiraz University of Medical Sciences

Liposomal and Viral Vectors for Gene Therapy of the Central Nervous System

A study of perceived factors affecting patients' participation in outpatient stroke physiotherapy exercise in Nigeria

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