Life cycle alterations of the micro-dielectrophoretic effects of cells

Peculiarities of live cells' interaction with micro- and nanoparticles

“…Pohl, published several papers about the interactions of live cells with dispersed particles [13][14][15][16][17]. The main purpose of these studies was to verify the hypothesis suggested in late 1960s by H. Frohlich who had proposed that live cells emit an AC electric field [18,19].…”

“…In an early paper, Pohl stated that the frequency of the cellular electric field must be at least 5 kHz (page 136 in [15]). Later, he and his group realized that all charges are screened in aqueous electrolyte solutions.…”

“…Pohl and his group at the Massachusetts Institute of Technology (MIT) [13][14][15][16][17]. They monitored the motion of small particles in the vicinity of biological cells to verify Frohlich's hypothesis [18,19] that implied that biological cells generated an AC electric field.…”

Cellular spinning in pulsed rotating electric fields

“…The evidence for natural cellular electrical oscillating fields arising from the study of the preference by live cells for polar over that for nonpolar particles in media of low conductivity (microdielectrophoresis) is rather general and is evidenced by bacterial, fungal, algal, avian, and mammalian cells (Pohl, 1980a(Pohl, , 1980b(Pohl, , 1980c(Pohl, , 1981a(Pohl, , 1981bPohl et al, 1981;Roy et al, 1981).…”

Fröhlich electromagnetic field generated by living cells: Computer results

“…The force field outside the cells is an oscillating electric field in nature, as is proved by microdielectrophoresis (Pohl, 1980a(Pohl, , 1980bRoy, et al, 1981;Pohl, et al, 1981). The number of attracted dielectric particles depends on the permittlvlty of the particles as well as on the conductivity of the liquid medium around the cells.…”