The sustainable development of agriculture is facing problems such as high resource consumption and serious environmental pollution. The development of circular economy model integrating planting and breeding (CEMIPB) has become an effective way to realize the sustainable development of agriculture. However, due to the large regional differences of circular models, references and comparability are generally lacking. Therefore, exploring economic benefit level and sustainability of CEMIPB through an effective evaluation model is necessary. Accordingly, this paper builds a methodological system for model evaluation and optimization based on the EM-LCA model and validates it with a typical CEMIPB in Fujian Province, China. By comparing the results of the EM-LCA and EMA models, the former effectively compensates for the deficiencies of the latter in terms of economic and environmental impact assessment, and the evaluation results can better reflect the actual situation of the system. Furthermore, sensitivity analysis is introduced to identify key processes and substances. Based on the reduce-reuse-recycle principle, several optimization suggestions, such as the corn and veterinary drugs, input reduction are put forward.The construction of the above methodology system can provide a new perspective for research in similar fields and provide a scientific basis for local government decision-making.