Life cycle assessment (LCA) is a vital tool for evaluating the environmental burden of solid waste. This study investigated the outcomes of selected studies that applied the LCA methodology in assessing the environmental consequences of solid waste management (SWM) systems in Africa. Thirteen process-based LCA studies on SWM were reviewed, drawing from established criteria in databases such as SCOPUS, Elsevier, and Google Scholar. These studies were distributed across various African countries, with three conducted in Mauritius and Nigeria each, two in Zimbabwe and South Africa each, and one in Tanzania, Ghana, and Uganda, respectively. The evaluated parameters included aspects such as goal and scope, functional unit, system boundary, impact assessment categories, and sensitivity analysis. The findings revealed that majority of the studies employed similar waste management scenarios to determine the most environment-friendly, yet they differed considerably in some parameters. Climate change and global warming were the most assessed impact categories. Municipal solid waste (MSW) and plastic waste were the leading waste categories. MSW typically comprises paper, bottles, metal, plastics, glass, organics, and mixed waste proportions. The study also stated that the lack of reliable data on solid waste was a significant challenge faced by African countries in LCA studies. The paper’s findings highlighted that a significant number of the studies, particularly in Nigeria, did not incorporate sensitivity analysis into their assessments, a crucial component for result interpretation. Consequently, the study emphasizes the importance of conducting more LCA research studies in African countries to produce pertinent data on SWM.