2020
DOI: 10.1159/000505785
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Life Cycle and Lensing of a Macular Microcyst

Abstract: Introduction: Microscopic details about retinal conditions can provide insight into pathological mechanisms, but these are ordinarily difficult to obtain in situ. We demonstrate how high-resolution imaging and optical modeling can be combined to reveal morphological features of a macular microcyst, offering insight into microcyst formation. Objective: To use adaptive optics scanning laser ophthalmoscopic (AOSLO) images to track a transient retinal microcyst and derive its 3-dimensional shape. Methods: A series… Show more

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“…Cone reflectivity measured in the confocal AOSLO can be a challenging metric for retinal health due to significant spatial and temporal variations. 4 Intra-cone reflectivity changes over time could be due to a multitude of factors, including light interference effects, 5 , 6 outer segment length changes due to disc shedding, 7 pigment density changes, 8 and optical waveguiding. 9 Inter-cone differences in reflectivity, however, are unrelated to cone type except under carefully controlled conditions, 10 and local reflectance angle differences are unlikely causes for large reflectivity differences.…”
mentioning
confidence: 99%
“…Cone reflectivity measured in the confocal AOSLO can be a challenging metric for retinal health due to significant spatial and temporal variations. 4 Intra-cone reflectivity changes over time could be due to a multitude of factors, including light interference effects, 5 , 6 outer segment length changes due to disc shedding, 7 pigment density changes, 8 and optical waveguiding. 9 Inter-cone differences in reflectivity, however, are unrelated to cone type except under carefully controlled conditions, 10 and local reflectance angle differences are unlikely causes for large reflectivity differences.…”
mentioning
confidence: 99%