Life expectancy in older adults with advanced cancer: Evaluation of a geriatric assessment-based prognostic model

Lund, Jennifer L.; Duberstein, Paul R.; Loh, Kah Poh; Gilmore, Nikesha; Plumb, Sandy; Lei, Lianlian; Keil, Alexander P.; Islam, Jessica Y.; Hanson, Laura C.; Giguere, Jeffrey K.; Vogel, Victor G.; Burnette, Brian L.; Mohile, Supriya G.

doi:10.1016/j.jgo.2021.08.009

Cited by 5 publications

(3 citation statements)

References 43 publications

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“…Over the years, new prognostic scoring systems have been devised and/or validated (Table 2) 16▪,18,23,24,28,40–62. These models often incorporate additional symptoms or laboratory values, which may be independent prognostic factors, to enhance the predictive power of the existing scoring systems.…”

Section: Instruments Available To Make a Prognosismentioning

confidence: 99%

Survival prediction in advanced cancer patients – a narrative review

Lee

Simone

2023

Current Opinion in Supportive &Amp; Palliative Care

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Purpose of reviewThe exploration for accurate ways to predict survival for advanced cancer patients continues to be a significant theme despite the advent of objective criteria and their combination with clinical criteria. The purpose of this article was to review some of the latest studies relating to prognostication and the capacity to predict survival during the terminal cancer stage. Recent findingsRecent studies show notable prognostication approaches using genetic tests and advanced computation methods such as machine learning, which we will summarize.

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Section: Instruments Available To Make a Prognosismentioning

confidence: 99%

Survival prediction in advanced cancer patients – a narrative review

Lee

Simone

2023

Current Opinion in Supportive &Amp; Palliative Care

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“…GA and management of identified deficits has been shown to decrease moderate to severe chemotherapy toxicity and improve completion rates of chemotherapy. It may also result in improved quality of life in those receiving systemic therapy [4][5][6][7]. Studies have shown that GA can be completed through self-administered surveys and/or electronically with minimal involvement from clinic staff other than for cognitive and objective physical functioning testing [8,9].…”

Section: Oncologic Assessment In Older Adultsmentioning

confidence: 99%

Key Considerations for the Treatment of Advanced Breast Cancer in Older Adults: An Expert Consensus of the Canadian Treatment Landscape

Jackson,

Curry,

Mariano

et al. 2023

Current Oncology

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The prevalence of breast cancer amongst older adults in Canada is increasing. This patient population faces unique challenges in the management of breast cancer, as older adults often have distinct biological, psychosocial, and treatment-related considerations. This paper presents an expert consensus of the Canadian treatment landscape, focusing on key considerations for optimizing selection of systemic therapy for advanced breast cancer in older adults. This paper aims to provide evidence-based recommendations and practical guidance for healthcare professionals involved in the care of older adults with breast cancer. By recognizing and addressing the specific needs of older adults, healthcare providers can optimize treatment outcomes and improve the overall quality of care for this population.

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“… 5-8 Further work in this same sample of patients by Lund et al examined the life expectancy in older adults with advanced cancer through the evaluation of a GA-based prognostic model. 9 To conduct the analysis Lund et al obtained patients’ vital status and date of death or end of follow-up data from the study forms, and this was subsequently verified by the patients’ community oncology practice. As part of the COACH study, survival was only assessed up to 1 year following enrollment onto the study.…”

mentioning

confidence: 99%