Life Functioning Assessment Inventory

Hui, Christy Y.; Li, Yuet-Keung; Leung, Kwok-fai; Tang, Joey; Wong, Gloria; Chang, Wing Chung; Chan, Sherry K.W.; H, Lee; Chen, Eric

doi:10.1037/t72173-000

Cited by 1 publication

(2 citation statements)

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“…The 1-year rate of relapse after the remission was calculated as 38.9% in the analysis report of the 5-year follow-up of 11 291 patients with schizophrenia published recently (Hudson, 2019). One-year relapse rates changed between 19.3 and 43.3% in these studies (Hui et al, 2013;Weret and Mukherjee, 2014;Xiao et al, 2015;Wu et al, 2017;Godin et al, 2018;Hudson, 2019). The 1-year relapse rate was found as 38.3% in patients with schizophrenia in this study similar to the literature.…”

Section: Discussionmentioning

confidence: 99%

“…It was also found that being younger than 35 increased the risk of early relapse by 2.089. Studies on the relationship between relapse and patient's age have conflicting results in the literature (Csernansky and Schuchart, 2002;Uçok et al, 2006;Ascher-Svanum et al, 2010;Alvarez-Jimenez et al, 2012;Hui et al, 2013;Lafeuille et al, 2013;Godin et al, 2018;Lee et al, 2018). There might be a few reasons for the conflicting results in the literature.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical and demographic factors associated with early relapse in patients with schizophrenia: a naturalistic observation study

Gündoğmuş¹,

Aydin

Öz

et al. 2021

International Clinical Psychopharmacology

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Schizophrenia is a chronic psychiatric disorder progressing in relapses. Identification of many factors that may potentially increase the risk of relapse will be an important step in preventing relapses. The aim of this study was to determine the rate of early relapse in patients with schizophrenia and possible risk factors related to early relapse. The sample of this prospective study with the naturalistic observation design consisted of 308 patients with schizophrenia. The cutoff value for early relapse was determined as 1 year. The mean age of participants was 37.38 ± 12.28 years and 66.6% of them were male (n = 205). The early relapse rate was 38.3%. The age younger than 35 [hazard ratio (HR) = 2.313; 95% confidence interval (CI), 1.518-3.526; P < 0.001], use of psychoactive substance (HR = 2.200; 95% CI, 1.407-3.440; P = 0.001), previous attempt of suicide (HR = 1.565; 95% CI, 1.028-2.384; P = 0.037), bad adherence to treatment (HR = 3.102; 95% CI, 1.358-7.086; P = 0.007), longacting injectables (LAIs) antipsychotics in the treatment (HR = 0.534; 95% CI, 0.351-0.812; P = 0.003), combination typical-atypical antipsychotics (HR = 0.326; 95% CI, 0.131-0.807; P = 0.015), number of episodes (HR = 1.088; 95% CI, 1.043-1.134), and the score on the Side Effect factor of the Clinical Global Impressions Scale (HR = 1.826; 95% CI, 1.357-2.458; P < 0.001) were identified as the independent predictors of early relapse. It is remarkable that treatment bad adherence, use of psychoactive substance, no LAIs antipsychotics included in the treatment, and the no presence of the combination of typical and atypical antipsychotics are alterable predictors of early relapse.

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