“…Another means of supporting biosignature exploration prior to, and during, a mission is by integrating survey techniques developed in microbial ecology. Past and recent NASA-funded rover field experiments testing microbial habitat and biosignature exploration strategies at the surface and in the subsurface of the Atacama Desert ( e.g., Wettergreen et al, 2005 , Cabrol et al, 2007a ) led to the development of ecological mapping techniques adapted to autonomous rover operations, and to the generation of predictive maps of habitat potential ( e.g., Hock et al, 2007 ; Warren-Rhodes et al, 2007a , 2007b , and unpublished data; Smith et al, 2007 ). This is typically an area where advances in detection algorithms and machine learning can bring new support to biosignature detection, including from orbit through, for example, the segmentation of hyperspectral imagery, correlation of orbital and surface spectra, novelty detection, multiscale adaptive sampling, data segmentation and superpixel clustering, and biohint probability mapping, among others ( e.g., Thompson et al, 2011 ; Candela et al, 2017 ).…”