Life stressors, hypertensive disorders of pregnancy, and preterm birth

Morgan, Nathaniel R.; Christensen, Kylie; Skedros, Gregory; Kim, Seungmin; Schliep, Karen C.

doi:10.1080/0167482x.2020.1778666

Cited by 12 publications

(7 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…101 Experiencing lifetime stressors (e.g., financial, emotional, relationship stress) was associated with an increased prevalence of hypertensive disorders of pregnancy. 118 Furthermore, having an occupation with high mental stress was associated with an increased risk of developing PRE-E in a sample of Canadian Women, 119 and job related stress during pregnancy increased the risk for PRE-E in a Black and White sample. 120 Social burden, defined as low social status and high psychosocial stress, was associated with PRE-E development in a cohort of pregnant German Women.…”

Section: Accepted Manuscriptmentioning

confidence: 93%

Trauma and Posttraumatic Stress Disorder as Important Risk Factors for Gestational Metabolic Dysfunction

Rocha,

Daniels,

Chandrasekaran

et al. 2024

Am J Perinatol

View full text Add to dashboard Cite

Gestational metabolic diseases adversely impact the health of pregnant persons and their offspring. Pregnant persons of color are impacted disproportionately by gestational metabolic disease, highlighting the need to identify additional risk factors contributing to racial-ethnic pregnancy-related health disparities. Trauma exposure and posttraumatic stress disorder are associated with increased risk for cardiometabolic disorders in non-pregnant persons, making them important factors to consider when identifying contributors to gestational metabolic morbidity and mortality health disparities. Here, we review current literature investigating trauma exposure and post-traumatic stress disorder as psychosocial risk factors for gestational metabolic disorders, inclusive of gestational diabetes, low birth weight and fetal growth restriction, gestational hypertension, and preeclampsia. We also discuss the physiological mechanisms by which trauma and PTSD may contribute to gestational metabolic disorders. Ultimately, understanding the biological underpinnings of how trauma and posttraumatic stress disorder, which disproportionately impact people of color, influence risk for gestational metabolic dysfunction is critical to developing therapeutic interventions that reduce complications arising from gestational metabolic disease.

show abstract

Section: Accepted Manuscriptmentioning

confidence: 93%

Trauma and Posttraumatic Stress Disorder as Important Risk Factors for Gestational Metabolic Dysfunction

Rocha,

Daniels,

Chandrasekaran

et al. 2024

Am J Perinatol

View full text Add to dashboard Cite

show abstract

“…Based on previous studies, stressful life events were categorized into four groups excluding stressor 3: partner-related stress (2,7,8,13), trauma-related stress (4,10,11,12), financial stress (5,6,9), and emotional stress (1,14) [4,[21][22][23]. * Question 3 was excluded because this question could be interpreted either as a positive or negative experience and/or consequence [24]. Participants who responded "yes" to any of the 13 stressors were coded as "yes" for psychosocial stress and their respective stressor categories.…”

Section: Psychosocial Stress Exposuresmentioning

confidence: 99%

Investigating Maternal Stress, Depression, and Breastfeeding: A Pregnancy Risk Assessment Monitoring System (2016–2019) Analysis

Dhaurali,

Dugat,

Whittler

et al. 2023

Healthcare

View full text Add to dashboard Cite

Breastfeeding is invaluable for postpartum physical healing and mental wellbeing, but psychosocial stress and depression impede such recovery processes. To inform future interventions and policies, associations between breastfeeding, maternal stress, and depression were examined. Data from the Pregnancy Risk Assessment Monitoring System (PRAMS) were analyzed (2016–2019). Logistic regression models were used to calculate adjusted odds ratios with 95% confidence intervals. Of the total sample (n = 95,820), approximately 88% of participants attempted breastfeeding. Our findings indicate that participants who experienced any form of stress had a slightly higher likelihood of breastfeeding compared to those without stress. Specifically, partner-related and financial-related stressors were significantly associated with increased odds of breastfeeding. However, no significant associations were observed trauma-related or emotional-related stressors and breastfeeding. Additionally, no significant association was found between depression at different stages (preconception, prenatal, and postpartum) and breastfeeding. A significant interaction effect was noted between having experienced any of the 13 stressors and Black race/ethnicity on breastfeeding odds. Similarly, significant interaction effects were observed between partner-related, trauma, financial, or emotional stressors and Black race/ethnicity. These findings emphasize the importance of considering various factors when promoting breastfeeding in diverse populations, and screening for psychosocial stress during postpartum visits. Our study recommends tailoring breastfeeding interventions to address the needs of Black mothers which could significantly improve maternal health and breastfeeding outcomes.

show abstract

“…Over time, the overactivation and interaction of these systems (neuroendocrine, autonomic nervous, and immune) lead to their dysfunction (sometimes referred to as toxic stress, wear and tear, or weathering) and stress-related disease ( 12 , 17 , 18 , 19 ). Regarding pregnancy and childbirth, exposure to adversity may increase risk for health conditions implicated in adverse birth outcomes, such as infection and pregnancy-induced hypertension, and/or directly alter maternal physiology associated with fetal development and timing of parturition ( 17 , 20 , 21 ).…”

Section: Cumulative Risk Stress and Healthmentioning

confidence: 99%

Life stressors, hypertensive disorders of pregnancy, and preterm birth

Cited by 12 publications

References 23 publications

Trauma and Posttraumatic Stress Disorder as Important Risk Factors for Gestational Metabolic Dysfunction

Trauma and Posttraumatic Stress Disorder as Important Risk Factors for Gestational Metabolic Dysfunction

Investigating Maternal Stress, Depression, and Breastfeeding: A Pregnancy Risk Assessment Monitoring System (2016–2019) Analysis

The contribution of racism-related stress and adversity to disparities in birth outcomes: evidence and research recommendations

Contact Info

Product

Resources

About