Although Wiener process models with the consideration of uncertainties, which are nonlinearity, random effects, and measurement errors, have been developed for lifetime prediction in the accelerated degradation test (ADT), they fail to describe the real degradation process because these models assume that the drift parameter correlates with the applied stress, while the diffusion parameter is constant. This paper put forward a nonlinear doubly Wiener constant-stress accelerated degradation model, where both diffusion and drift parameters were compatible with the applied stress according to the acceleration factor constant principle. When degradation data were available, we obtained the unknown parameters by applying a maximum likelihood estimation (MLE) algorithm in the constant-stress ADT (CSADT) model taking uncertainties into account. In addition, the proposed model’s effectiveness was validated through an illustrative example, and an application to the traveling wave tube (TWT) was carried out to demonstrate the superiority of our model in practical applications.