2011
DOI: 10.1155/2011/140381
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Life-Threatening Laryngeal Edema and Hyponatremia during Hysteroscopy

Abstract: We report on a 43-year-old patient undergoing a hysteroscopic myomectomy. After 80 minutes of operation, the patient developed laryngeal edema, requiring emergency tracheostomy. Hyponatremia (serum sodium 78 mmoL/L) indicated an irrigation fluid absorption. The patient developed shock, acute respiratory distress syndrome, acute renal failure, and diffuse intravascular coagulopathy. Resuscitation including continuous venovenous hemodiafiltration was required. Finally, the patient made a full clinical recovery. … Show more

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Cited by 11 publications
(10 citation statements)
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“…With the development of resectoscopes using bipolar current the use of isotonic electrolyte solutions such as Ringer’s lactate or 0.9% saline may be used as distension media 3. Systemic absorption of some of the distension fluid medium is expected, with the average amount of fluid absorbed during operative hysteroscopy cases being approximately 400–600 mL 4. Intravascular absorption of fluid is driven by (1) increasing the hydrostatic pressure gradient between the distension fluid and the vasculature, and (2) increasing the surface area of vascular beds exposed to the distension fluid.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…With the development of resectoscopes using bipolar current the use of isotonic electrolyte solutions such as Ringer’s lactate or 0.9% saline may be used as distension media 3. Systemic absorption of some of the distension fluid medium is expected, with the average amount of fluid absorbed during operative hysteroscopy cases being approximately 400–600 mL 4. Intravascular absorption of fluid is driven by (1) increasing the hydrostatic pressure gradient between the distension fluid and the vasculature, and (2) increasing the surface area of vascular beds exposed to the distension fluid.…”
Section: Discussionmentioning
confidence: 99%
“…OHIA syndrome can present with myriad signs and symptoms. Manifestations may include nausea, vomiting, headache, weakness, pulmonary edema, acute respiratory distress syndrome, laryngeal edema, cerebral edema, hyponatremia, hypocalcemia, diffuse intravascular coagulation and rhabdomyolysis 1,2,4,8,9. This condition is not uncommon and is usually transient and mild in severity; however, it can be life-threatening 10.…”
Section: Discussionmentioning
confidence: 99%
“…A correction rate of 25 mEq/L is generally recommended within 48 h until the sodium in the serum is above 120 mEq/L, but without reaching normal or hypernatremic levels [ 31 , 32 ]. Despite this, most publications report significantly higher correction rates [ 18 , 20 , 21 , 33 ], even correcting as rapidly as the initial sodium level decreased [ 27 ]. Encephalopathy or pontine myelysis did not occur in any of these cases and patients were reported to have recovered fully after therapy.…”
Section: Discussionmentioning
confidence: 99%
“…However, these hypoosmolar, electrolyte-free media can create fluid and electrolyte disturbances if absorbed in excess. 30,38 Neurological adverse events including hypotonic encephalopathy have been reported more often in reproductive aged women than in postmenopausal women. 37 The sodium-potassium ATP-ase pump is responsible for shunting sodium and, indirectly, water out of the cell.…”
Section: Low-viscosity Fluidsmentioning
confidence: 99%