Life-threatening manifestation of cutaneous leukocytoclastic vasculitis

Runowska, Marta; Majewski, Dominik; Puszczewicz, Mariusz

doi:10.5114/ada.2021.106214

Cited by 1 publication

(1 citation statement)

References 9 publications

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“…Subsequently, the allergic reaction induces formation of immune complex deposits in the skin capillaries and small vascular endothelium, resulting in the skin lesions of ACV[ 11 ]. The treatment choice depends on the severity of the patient's condition and can range from antihistamines to corticosteroids to immunosuppressive drugs[ 12 , 13 ]. However, glucocorticoids are conventionally the first choice of drugs used in clinical practice.…”

Section: Discussionmentioning

confidence: 99%

Danggui Sini decoction treatment of refractory allergic cutaneous vasculitis: A case report

Chen¹,

Wu²,

Wang³

et al. 2022

World J Clin Cases

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BACKGROUND Allergic cutaneous vasculitis (ACV) is a difficult disease to treat. At present, there is no effective treatment for this condition. Traditionally, immunosuppressants and hormones have been primarily used in its management, but the treatment effect is suboptimal, and it has several side effects. CASE SUMMARY We present the case of a 19-year-old woman who presented at our hospital with a four-year history of symmetric skin lesions mainly affecting her lower extremities. She had previously undergone treatment with prednisolone acetate, cetirizine hydrochloride, and loratadine tablets but had not experienced any relief in her condition. Thereafter, she was treated with oral traditional Chinese medicine. Her skin damage gradually improved within two months of treatment initiation. After six months, the skin ulcers had completely subsided. No evidence of skin ulcer recurrence was observed during the subsequent follow-up. This report presents the first case of a female patient who received oral Danggui Sini decoction for the treatment of ACV. CONCLUSION Danggui Sini decoction may be a promising oral treatment for ACV patients.

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Section: Discussionmentioning

confidence: 99%