Lifestyle and nutrition peculiarities as risk factors for precancerous skin lesions and premature skin ageing in Latvian citizens

Janovska, Jana; Voicehovska, Jūlija

doi:10.1016/j.jomh.2011.08.077

Cited by 1 publication

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“…It is important to note, however, that younger biological appearance among elders does not equal fitness. 1,[7][8][9][10] The bone, like any other biological structure in the human body, is dynamic. On a molecular level, the bone cells-namely the osteoblasts and osteoclasts-are continuously remodeling the bone structure.…”

Section: Introductionmentioning

confidence: 99%

Bioanthropological and Biomechanical Perspectives on Skeletal Senescence Variation: A Literature Review

Alaydrus,

Jauhari

2024

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Background: Senescence is the deterioration of the body’s biological and physiological function throughout later life. Senescent populations are more prone to diseases, though other than osteoporosis, skeletal senescence is a less discussed topic in Indonesia. Furthermore, a global and national increase in the aging population showed that they will be a major group in society, thus raising the urgency to review this matter. This study aims to comprehend the physiological and biomechanical mechanisms of skeletal senescence, as well as senescent variations in a certain sex or population affinity. Literature Review: Age-related skeletal cellular death and imbalance contribute to bone damage in elders. Senescence also affects skeletal biomechanics, expressed in increased bone porosity and brittleness. Stresses in aged bone risk straining above its elastic limit and causing fractures due to its inability to tolerate stresses. The loss of sex hormones is related to skeletal senescence, especially in females, though the effects of testosterone on skeletal senescence are underresearched. Dietary change, estrogen replacement therapy, and calcitonin consumption are effective measures in reducing the effects of osteoporosis. Variations were found in the bone aging process in different populations, especially regarding bone mineral density loss in white, African-American, Asian, and Hispanic populations. Summary: Specific population-based healthcare services in geriatrics and gerontology are highly suggested to ensure inclusive healthcare for every aged individual. Due to the minimum data about bone aging in Indonesia (other than osteoporosis), the authors encourage data procurement on local populations to create more suitable medical guidelines for elders in Indonesia.

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