Lifestyle factors as predictors of nonadherence to statin therapy among patients with and without cardiovascular comorbidities

Secondary CV Prevention in South America in a Community Setting: The PURE Study

“…In a meta-analysis on statin adherence, women had 10% greater odds of nonadherence than did men [46], and, similarly, patients who were hospitalized for CVD event or procedure and elderly patients after acute MI [27,30] were more likely to use statins, as suggested in our analysis. Some studies have suggested that sicker patients are less likely to receive evidence-based therapies [21,47]. However, our data suggest that higher risk (e.g., diabetic, older, and obese) patients have higher rates of use of these therapies.…”

Low statin use in adults hospitalized with acute coronary syndrome

“…Other studies have similarly found that former smokers are particularly adherent to statin therapy while smokers have lower rates of long-term statin use, possibly due to multiple confounders such as socioeconomic status 28,29 . Conversely, because current smoking is a strong cardiovascular risk factor, current smokers are more likely to have a statin indication.…”

Predictors of first-year statin medication discontinuation: A cohort study

“…The questionnaires involved demographic characteristics, lifestyle factors, and health status, and the average response rate was 70%. We linked the survey data to data from national health registers using unique personal identification numbers as in our earlier studies 34, 35. Among the respondents, there were 11,949 participants who had initiated statin medication between 1 January, 1998 and 31 December, 2010.…”

“…We assessed lifestyle factors using standard questionnaire measurements 34, 35. We requested the participants' smoking status (none, former, current) and calculated body mass index using self-reported weight and height.…”