Lifestyle Interventions for Diabetes Prevention in South Asians: Current Evidence and Opportunities

Weber, Mary Beth; Gujral, Unjali P.; Jagannathan, Ram; Shah, Megha

doi:10.1007/s11892-021-01393-5

Cited by 5 publications

(2 citation statements)

References 64 publications

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“…565 Type 2 diabetes mellitus (T2DM) Lifestyle intervention is an effective and feasible method for reducing diabetes risk. 566 For example, weight loss resulting from dietary and physical activity interventions effectively reduces the incidence of T2DM. 567 Pancreatic β cell and adipocyte senescence leads to insulin resistance and worsens metabolic homeostasis.…”

Section: Atherosclerosismentioning

confidence: 99%

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Guo

Huang

Dou

et al. 2022

Sig Transduct Target Ther

487

160

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Aging is a gradual and irreversible pathophysiological process. It presents with declines in tissue and cell functions and significant increases in the risks of various aging-related diseases, including neurodegenerative diseases, cardiovascular diseases, metabolic diseases, musculoskeletal diseases, and immune system diseases. Although the development of modern medicine has promoted human health and greatly extended life expectancy, with the aging of society, a variety of chronic diseases have gradually become the most important causes of disability and death in elderly individuals. Current research on aging focuses on elucidating how various endogenous and exogenous stresses (such as genomic instability, telomere dysfunction, epigenetic alterations, loss of proteostasis, compromise of autophagy, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, deregulated nutrient sensing) participate in the regulation of aging. Furthermore, thorough research on the pathogenesis of aging to identify interventions that promote health and longevity (such as caloric restriction, microbiota transplantation, and nutritional intervention) and clinical treatment methods for aging-related diseases (depletion of senescent cells, stem cell therapy, antioxidative and anti-inflammatory treatments, and hormone replacement therapy) could decrease the incidence and development of aging-related diseases and in turn promote healthy aging and longevity.

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Section: Atherosclerosismentioning

confidence: 99%

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Guo

Huang

Dou

et al. 2022

Sig Transduct Target Ther

487

160

View full text Add to dashboard Cite

show abstract

“…Lifestyle interventions have primarily been recognized as a fundamental strategy to prevent metabolic diseases, especially diabetes mellitus [100,101]. Recent studies demonstrated that water intake or hydration status play a unique role in metabolic diseases.…”

Section: Metabolic Healthmentioning

confidence: 99%

Hydration Status in Older Adults: Current Knowledge and Future Challenges

Xiao

Zhang

2023

Nutrients

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Adequate hydration is essential for the maintenance of health and physiological functions in humans. However, many older adults do not maintain adequate hydration, which is under-recognized and poorly managed. Older adults are more vulnerable to dehydration, especially those living with multiple chronic diseases. Dehydration is associated with adverse health outcomes in older adults, and acts as an independent factor of the hospital length of stay, readmission, intensive care, in-hospital mortality, and poor prognosis. Dehydration is a prevalent health problem in older adults, accounting for substantial economic and social burden. This review attempts to provide current knowledge of hydration including patterns of body water turnover, the complex mechanisms behind water homeostasis, the effects of dehydration on the health of the body, and practical guidance for low-intake dehydration in older adults.

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Effectiveness of a dietician-led intervention in reducing glycated haemoglobin among people with type 2 diabetes in Nepal: a single centre, open-label, randomised controlled trial

Sunuwar,

Nayaju,

Dhungana

et al. 2023

The Lancet Regional Health - Southeast Asia

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Lifestyle Interventions for Diabetes Prevention in South Asians: Current Evidence and Opportunities

Cited by 5 publications

References 64 publications

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

Hydration Status in Older Adults: Current Knowledge and Future Challenges

Effectiveness of a dietician-led intervention in reducing glycated haemoglobin among people with type 2 diabetes in Nepal: a single centre, open-label, randomised controlled trial

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