Lifestyle, Occupational, and Reproductive Factors in Relation to Pancreatic Cancer Risk

Abstract

Multiple tobacco consumption methods, passive smoking, pesticide exposures, and diabetes are associated with an increased risk for pancreatic cancer. Prolonged lactation and increased parity are associated with a reduced risk for pancreatic cancer.

Reproductive factors and pancreatic cancer risk: a Norwegian cohort study

“…No significant relation with breastfeeding was found in a cohort study of younger women with shorter overall breastfeeding times (Skinner et al, 2003), while a case -control study, including extended breastfeeding periods, showed an inverse relation (Lo et al, 2007) consistent with our results.…”

“…Others showed a higher (Karlson et al, 1998;Navarro Silvera et al, 2005) or lower (Hanley et al, 2001;Teras et al, 2005) risk among women with many children only or even no association with parity (Duell and Holly, 2005;Prizment et al, 2007). Breastfeeding was covered in only two studies (Skinner et al, 2003;Lo et al, 2007) while menstrual factors have shown inconclusive findings (Prizment et al, 2007).…”

Tobacco smoking in Egypt: a scoping literature review of its epidemiology and control measures

“…A case-control study by An-chi lo et al (39) showed that smoking increased the risk of pancreatic cancer with an OR of 4.5 (95%CI [1. 9-10.7]) for smokers who ever smoked cigarettes only, and an OR of 7.8 (95%CI [3.0 to 20.6]) for smokers who ever used multiple types of tobacco smoking.…”

Secondhand Tobacco Smoke

“…pdf) and three case-control (Villeneuve et al, 2004;Hassan et al, 2007;Lo et al, 2007; the former two studies are summarized in Table 2.18 available at http://monographs.iarc.fr/ENG/ Monographs/vol100E/100E-02-Table2.18.pdf).…”

“…(RR 1.2 (95%CI: 0.45-3.1) and 1.21 (95%CI: 0.60-2.44) respectively). Lo et al (2007) reported an odd ratio of 6.0 (95%CI: 2.4 −14.8) for never smokers (both sexes combined) exposed to second-hand tobacco smoke in Egypt. [The Working Group noted the small numbers of cases, the use of hospital controls and the small proportion of the cases (35%) with histopathological confirmation.…”