Ligand-exchange chromatography of racemates

Davankov, V. A.; Рогожин, С. В.; Semechkin, A.V.; Sachkova, T.P.

doi:10.1016/s0021-9673(01)91842-4

Cited by 76 publications

(9 citation statements)

References 10 publications

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“…Thus, hypercrosslinked (HXL) polymers become interesting as SPE sorbents since they have high specific surface areas (above 1000 m 2 g −1 ) and tuneable chemistry, in combination with a high micropore content . Hypercrosslinked polymers, first introduced by Davankov et al . have a number of features that render them attractive for exploitation as SPE sorbents, with a number of recent publications focusing upon the preparation of hypercrosslinked polymers in appropriate physical formats and with ion‐exchange groups to enable selective extractions.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of poly(acrylonitrile‐co‐divinylbenzene‐co‐vinylbenzyl chloride)‐derived hypercrosslinked polymer microspheres and a preliminary evaluation of their potential for the solid‐phase capture of pharmaceuticals

Subri

Cormack

Jamil

et al. 2017

J of Applied Polymer Sci

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Poly[acrylonitrile (AN)‐co‐divinylbenzene (DVB)‐co‐vinylbenzyl chloride (VBC)] terpolymers were synthesized by precipitation polymerization in the form of porous polymer microspheres. The poly(AN‐co‐DVB‐co‐VBC) polymers were then hypercrosslinked, via a Friedel‐Crafts reaction with FeCl3 in nitrobenzene, to provide a significant uplift in the specific surface areas of the polymers. FTIR spectra of the hypercrosslinked poly(AN‐co‐DVB‐co‐VBC)s showed that the chloromethyl groups derived from VBC were consumed by the Friedel‐Crafts reactions, which was consistent with successful hypercrosslinking. Hypercrosslinking installed a number of new, small pores into the polymers, as evidenced by a dramatic increase in the specific surface areas upon hypercrosslinking (from ∼530 to 1080 m2 g−1). The hypercrosslinked polymers are very interesting for a range of applications, not least of all for solid‐phase extraction (SPE) work, where the convenient physical form of the polymers (beaded format), their low mean particle diameters, and narrow particle size distributions, as well as their high specific surface areas and polar character (arising from the AN residues), make them attractive candidates as SPE sorbents. In this regard, in a preliminary study one of the hypercrosslinked polymers was utilized as an SPE sorbent for the capture of the polar pharmaceutical diclofenac from a polar environment. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45677.

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Section: Introductionmentioning

confidence: 99%

Synthesis of poly(acrylonitrile‐co‐divinylbenzene‐co‐vinylbenzyl chloride)‐derived hypercrosslinked polymer microspheres and a preliminary evaluation of their potential for the solid‐phase capture of pharmaceuticals

Subri

Cormack

Jamil

et al. 2017

J of Applied Polymer Sci

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“…However, since the desired online screen required increased efficiency and stability, relative to the performance of Ni-NTA and Ni-IDA, a commercially available high performance liquid chromatography chiral ligand exchange column was used in these studies. Chiral ligand exchange chromatography has been extensively used for the enantioselective separations of amino acid enantiomers [13,14]. The technique employs an immobilized chiral selector, such as proline, and utilizes Cu 2+ as the coordinating metal ion.…”

Section: Introductionmentioning

confidence: 99%

The synthesis and initial characterization of an immobilized DNA unwinding element binding (DUE-B) protein chromatographic stationary phase

Moaddel

Price

Juteau³

et al. 2005

Journal of Chromatography B

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“…Soc., Perkin Trans., 1, 1182-4 (1972). (102) Veibel, S., "Determination of Hydroxyl Groups," Academic Press, New York, N.Y., 1972.…”

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Ion exchange

Walton¹

1974

Anal. Chem.

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Harold F. Walton joined the staff of the University of Colorado in 1947. His research interests in ion exchange date from 1938 when he went to work for the Permutit Co. as a research chemist; from there he went to Northwestern University in 1940. He obtained the BA and DPhil degrees at Oxford University. He Is the author of three textbooks on inorganic and analytical chemistry and coauthor with William Rieman III of "Ion Exchange in Analytical Chemistry" published in 1970. He has contributed chapters on the physical and analytical chemistry of ion exchange to several cooperative works. In 1961 he was chairman of the Gordon Research Conference on Ion Exchange. Dr. Walton spent the 1966-67 academic year and half of 1970 as a Fulbright visiting professor at the University of Trujillo, Peru. He Is a member of the Advisory Board of Analytical Chemistry.has chapters on ion exchange in nonaqueous and mixed solvents by Marcus, on ligand-exchange chromatography by Walton, and on liquid ion exchange technology by Kunin; Volume 5 has accounts of inorganic ion exchangers by Clearfield, Nancollas, and Blessing; of ion exchange in elemental analysis by Strelow; and on pellicular ion exchange resins by Horvath. A good short account of ion exchange in analytical chemistry is that by Inczedy in the Chemical Rubber Publishing Company's review series (A6). The International Union of Pure and Applied Chemistry has published the report of a committee on ion-exchange nomenclature, consisting of O. Samuelson, E. Bayer, and F. G. Helfferich (A7).In the Russian language, two books on ion exchange have appeared (A9, A 28). Both books were reviewed in the Russian Journal of Analytical Chemistry (Zh. Anal. Khim.). Another significant Russian book is that edited by Sladkov (A 29), which has a chapter by Davankov, Rogozhin, and Semechkin on ligand-exchange chromatography and another by Rogozhin, Davankov, and Peslayakas on the chromatographic separation of optical isomers. Reviews on chelating ion exchangers (A 23) and complex-ion formation in exchange resins (A27) have also appeared. A paper by Gurvich (288) describes the use of organic complexing agents incorporated into absorbants like charcoal.A German review (A20) is aptly titled "Ion Exchangers -Active Polymers." Recent progress in ion-exchange chromatography is reviewed in Japanese (A 14). An English-language book reflecting the author's own research and interest is that by Muzzarelli (A22).The latest volume of "Chromatographic Reviews," now published as an integral part of the Journal of Chromatography, includes two chapters on a very timely topic, the

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Ligand-exchange chromatography of racemates

Cited by 76 publications

References 10 publications

Synthesis of poly(acrylonitrile‐co‐divinylbenzene‐co‐vinylbenzyl chloride)‐derived hypercrosslinked polymer microspheres and a preliminary evaluation of their potential for the solid‐phase capture of pharmaceuticals

Synthesis of poly(acrylonitrile‐co‐divinylbenzene‐co‐vinylbenzyl chloride)‐derived hypercrosslinked polymer microspheres and a preliminary evaluation of their potential for the solid‐phase capture of pharmaceuticals

The synthesis and initial characterization of an immobilized DNA unwinding element binding (DUE-B) protein chromatographic stationary phase

Ion exchange

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