2023
DOI: 10.1016/j.snb.2023.134002
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Light-controlled and glutathione-stimulative DNA walking motor under the collaborative carrying of MOF for self-powered sensing and drug release in living organisms

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Cited by 6 publications
(1 citation statement)
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“…In the past few years, with the joint efforts of various scientists, breakthroughs have been made in the application of DNA motors for biomolecule detection in living systems. For example, Le et al presented for the first time the construction of a self-powered DNAzyme motor for live cell microRNA imaging . Similarly, other autonomous DNAzyme motors were designed for the visualization of intracellular biomolecules. Additionally, entropy-driven DNA motors have been used for monitoring intracellular microRNAs, while DNA motors powered by adenosine triphosphate (ATP) molecules have been developed for intracellular microRNA imaging. Despite encouraging progress in this area, the amplification capacities of these DNA motors remain limited owing to the fact that the products generated from the walking process are unable to feedback into the original DNA motor systems, thereby resulting in inefficient signal amplification. Consequently, it has not been possible to further improve the sensitivities of these systems, thereby hindering their applications in the detection and imaging of ultralow-concentration molecular biomarkers.…”
mentioning
confidence: 99%
“…In the past few years, with the joint efforts of various scientists, breakthroughs have been made in the application of DNA motors for biomolecule detection in living systems. For example, Le et al presented for the first time the construction of a self-powered DNAzyme motor for live cell microRNA imaging . Similarly, other autonomous DNAzyme motors were designed for the visualization of intracellular biomolecules. Additionally, entropy-driven DNA motors have been used for monitoring intracellular microRNAs, while DNA motors powered by adenosine triphosphate (ATP) molecules have been developed for intracellular microRNA imaging. Despite encouraging progress in this area, the amplification capacities of these DNA motors remain limited owing to the fact that the products generated from the walking process are unable to feedback into the original DNA motor systems, thereby resulting in inefficient signal amplification. Consequently, it has not been possible to further improve the sensitivities of these systems, thereby hindering their applications in the detection and imaging of ultralow-concentration molecular biomarkers.…”
mentioning
confidence: 99%