Light-scattering signals from nanoparticles in biochemical assay, pharmaceutical analysis and biological imaging

Analysis of pharmaceutical products and herbal medicines using ambient mass spectrometry

“…Pharmaceutical analysis, as an important approach to understand the active pharmaceutical ingredients and impurities, to ensure the efficacy and safety, as well as to develop methodologies for quality assessment and control of pharmaceutical products and herbal medicines, has been a hot research topic in recent years. Huge efforts have been spent in this field, with different techniques including optical spectroscopy [5][6][7], chromatography [7][8][9][10][11][12][13][14], and mass spectrometry (MS) [12][13][14][15][16][17][18][19][20], etc., have been developed in the past several decades. The chromatography and chromatography coupled with MS techniques have been proven to be the powerful tools due to their properties of excellent sensitivity, desirable specificity, and reasonable qualitative and quantitative capability.…”

Hybrid nanosensor for colorimetric and ultrasensitive detection of nuclease contaminations

“…However, the simple test interpretation must be supported by a smart test design, to ensure reliable and reproducible performances and an unequivocal readout of the results, and to reach high sensitivity and specificity. Nanomaterials are key elements in the development of detection sensors, thanks to their countless potentialities [9][10][11][12][13][14][15][16][17][18] . In particular, gold nanoparticles (AuNPs) offer real advantages in the design of colorimetric sensors.…”

Resonance Rayleigh scattering method for determination of 2-mercaptobenzothiazole using gold nanoparticles probe

“…Resonance Rayleigh scattering takes place when the wavelength of Rayleigh scattering is located at or close to the molecular absorption band. The properties of scattered light depend on the size, composition, shape, homogeneity of the nanoparticles, and refractive index of the medium [26,27].…”