ABS TRACT Lightning strike is one of the causes of injury and death caused by environmental or natural events. Deaths can be seen after lightning strikes, also many different organ systems can be temporarily or permanently affected. Lightning strike can cause damage to many organ systems such as musculoskeletal system, cardiovascular system, neurological system, dermatological system, visual and hearing. The patients must be evaluated for multi-organ system involvement after lightning strike and the treatment must be structured with a multidisciplinary approach. An appropriate rehabilitation plan should be made according to the clinical conditions of the patients. Here, we present a case series of 4 patients with different organ or system involvement after lightning strikes who were followed up with a multidisciplinary approach and rehabilitation programme.