2012
DOI: 10.1016/j.fitote.2011.11.008
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Lignans from the heartwood of Streblus asper and their inhibiting activities to Hepatitis B virus

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Cited by 42 publications
(16 citation statements)
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“…Kong et al (2013) discovered that UA significantly suppressed the replication of HCV genotype 1b replicon and HCV genotype 2a JFH1 virus by suppressing HCV NS5B RdRp activity as noncompetitive inhibitors. Li et al (2012) also confirmed that UA showed inhibitory activity for HBV, another pathogenic virus, with IC 50 values of 89.91 lM for HBsAg and 97.61 lM for HBeAg at no cytotoxicity. Wu et al (2011) supported that UA could break hepatitis B virus X protein (HBx)-mediated tumourigenic effects.…”
Section: Introductionsupporting
confidence: 64%
“…Kong et al (2013) discovered that UA significantly suppressed the replication of HCV genotype 1b replicon and HCV genotype 2a JFH1 virus by suppressing HCV NS5B RdRp activity as noncompetitive inhibitors. Li et al (2012) also confirmed that UA showed inhibitory activity for HBV, another pathogenic virus, with IC 50 values of 89.91 lM for HBsAg and 97.61 lM for HBeAg at no cytotoxicity. Wu et al (2011) supported that UA could break hepatitis B virus X protein (HBx)-mediated tumourigenic effects.…”
Section: Introductionsupporting
confidence: 64%
“…1 In current pharmacologic research, S. asper has exhibited antilarial, 3,4 antimicrobial, 5 antimalarial, 6 anti-HBV, 7,8 antidiabetic, 9 cytotoxic, and antineoplastic activities. [10][11][12] The chemical constituents of S. asper including avo-noids, 7,13 volatile oils, 14 phenolic acids, 4 fatty acids, 15 phenylpropanoids, 7,8,16,17 and cardiac glycosides [18][19][20][21] have been extensively studied. Numerous cardiac glycosides have also been discovered from the roots of this plant.…”
Section: Introductionmentioning
confidence: 99%
“…[1] In this study, we use the MS n spectra to obtain the fragmentation mechanisms of the compounds isolated from Streblus asper. [2,3] Streblus asper of the family Moraceae is a medicinal herb mainly distributed in South China and Southern Asia. [2,4] It is used as an antibacterial agent and for the treatment of HBV infection, fever, dysentery, toothache, gingivitis, inflammation, etc.…”
mentioning
confidence: 99%
“…[2,3] Streblus asper of the family Moraceae is a medicinal herb mainly distributed in South China and Southern Asia. [2,4] It is used as an antibacterial agent and for the treatment of HBV infection, fever, dysentery, toothache, gingivitis, inflammation, etc. [3,5] This plant is known to produce steroids, cardiac glycosides, flavonoids, triterpenoids and lignans.…”
mentioning
confidence: 99%