Lignin-based hydrogels: A review of preparation, properties, and application

Yang, Meng; Lü, Jie; Cheng, Yi; Li, Qiang; Wang, Haisong

doi:10.1016/j.ijbiomac.2019.05.198

Cited by 230 publications

(121 citation statements)

References 128 publications

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“…For example, Meng et al described lignin-based hydrogels, which were by-products of the pulp and paper industry and were selected for their biocompatibility, biodegradability, and nontoxicity characteristics. Lignin-based hydrogels can serve as absorbers for heavy metal ions as well as biosensors and intelligent materials [ 29 ]. Moreover, hydrogels based on chitosan are widely used as dressing materials.…”

Section: Introductionmentioning

confidence: 99%

Physicochemical Investigations of Chitosan-Based Hydrogels Containing Aloe Vera Designed for Biomedical Use

et al. 2020

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In this work, synthesis and investigations on chitosan-based hydrogels modified with Aloe vera juice are presented. These materials were synthesized by UV radiation. Investigations involved analysis of chemical structure by FTIR spectroscopy, sorption properties in physiological liquids, strength properties by texture analyzer, surface topography by Atomic Force Microscopy (AFM technique), and in vitro cytotoxicity by MTT test using L929 murine fibroblasts. Particular attention was focused both on determining the impact of the amount and the molecular weight of the crosslinker used for the synthesis as well as on the introduced additive on the properties of hydrogels. It was proven that modified hydrogels exhibited higher swelling ability. Introduced additive affected the tensile strength of hydrogels—modified materials showed 23% higher elongation. The greater amount of the crosslinker used in the synthesis, the more compact the structure, leading to the lower elasticity and lower sorption of hydrogels was reported. Above 95%, murine fibroblasts remained viable after 24 h incubation with hydrogels. It indicates that tested materials did not exhibit cytotoxicity toward these lines. Additionally, materials with Aloe vera juice were characterized by lower surface roughness. Conducted investigations allowed us to state that such modified hydrogels may be considered as useful for biomedical purposes.

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Section: Introductionmentioning

confidence: 99%

Physicochemical Investigations of Chitosan-Based Hydrogels Containing Aloe Vera Designed for Biomedical Use

et al. 2020

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“…contain many different functional groups (hydroxyls, carboxyls, carbonyls and methoxyls) as active sites, in preparation of functional hydrogels both by physical crosslinking with hydrophilic polymers by H-bonding and also by, polymerization, copolymerization, ATRP and reversible addition-fragmentation transfer (RAFT) polymerization, chemical crosslinking, crosslinking grafted lignin and monomers etc. [436][437][438].…”

Section: Hybrid Hydrogels Containing Lignin For Biomedical Applicationsmentioning

confidence: 99%

New Developments in Medical Applications of Hybrid Hydrogels Containing Natural Polymers

Vasile¹,

Pamfil²,

Stoleru³

et al. 2020

Molecules

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New trends in biomedical applications of the hybrid polymeric hydrogels, obtained by combining natural polymers with synthetic ones, have been reviewed. Homopolysaccharides, heteropolysaccharides, as well as polypeptides, proteins and nucleic acids, are presented from the point of view of their ability to form hydrogels with synthetic polymers, the preparation procedures for polymeric organic hybrid hydrogels, general physico-chemical properties and main biomedical applications (i.e., tissue engineering, wound dressing, drug delivery, etc.).

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“…The presence of dyes and other organic pollutants in water represent a hazardous for the aquatic species. The phenolic rings present in the lignin derivatives could enhance the retention of these organic pollutants due to π-π reaction with aromatic pollutants [84]. Furthermore, the pH sensitivity of the lignin and/or its counterpart monomers could also facilitate the absorption of the contaminants by the hydrogel.…”

Section: Hydrogels Fo Water Remediationmentioning

confidence: 99%

Lignin-Based Hydrogels: Synthesis and Applications

et al. 2020

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Polymers obtained from biomass are an interesting alternative to petro-based polymers due to their low cost of production, biocompatibility, and biodegradability. This is the case of lignin, which is the second most abundant biopolymer in plants. As a consequence, the exploitation of lignin for the production of new materials with improved properties is currently considered as one of the main challenging issues, especially for the paper industry. Regarding its chemical structure, lignin is a crosslinked polymer that contains many functional hydrophilic and active groups, such as hydroxyls, carbonyls and methoxyls, which provides a great potential to be employed in the synthesis of biodegradable hydrogels, materials that are recognized for their interesting applicability in biomedicine, soil and water treatment, and agriculture, among others. This work describes the main methods for the preparation of lignin-based hydrogels reported in the last years, based on the chemical and/or physical interaction with polymers widely used in hydrogels formulations. Furthermore, herein are also reviewed the current applications of lignin hydrogels as stimuli-responsive materials, flexible supercapacitors, and wearable electronics for biomedical and water remediation applications.

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Lignin-based hydrogels: A review of preparation, properties, and application

Cited by 230 publications

References 128 publications

Physicochemical Investigations of Chitosan-Based Hydrogels Containing Aloe Vera Designed for Biomedical Use

Physicochemical Investigations of Chitosan-Based Hydrogels Containing Aloe Vera Designed for Biomedical Use

New Developments in Medical Applications of Hybrid Hydrogels Containing Natural Polymers

Lignin-Based Hydrogels: Synthesis and Applications

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