Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications

Abstract

Over the past decade, lignin-based porous biomaterials have been found to have strong potential applications in the areas of drug delivery, tissue engineering, wound dressing, pharmaceutical excipients, biosensors, and medical devices. Lignin-based porous biomaterials have the addition of lignin obtained from lignocellulosic biomass. Lignin as an aromatic compound is likely to modify the materials’ mechanical properties, thermal properties, antioxidant, antibacterial property, biodegradability, and biocompatibility. The size, shape, and distribution of pores can determine the materials’ porous structure, porosity, surface areas, permeability, porosity, water solubility, and adsorption ability. These features could be suitable for medical applications, especially controlled drug delivery systems, wound dressing, and tissue engineering. In this review, we provide an overview of the current status and future potential of lignin-based porous materials for medical and pharmaceutical uses, focusing on material types, key properties, approaches and techniques of modification and fabrication, and promising medical applications.

Nano‐Strategies for Lignin Biomaterials toward Cancer Therapy

“…focused on the properties and chemical modifications of lignin‐based nanomaterials for biomedical applications, [ 14 ] Nan et al. reviewed lignin‐based porous biomaterials for both application fields, [ 23 ] and Deng et al. summarized the studies on the synthesis methods, properties, and applications of NL.…”

Antimicrobial and antioxidant supramolecular ionic liquid gels from biopolymer mixtures

“…This porous structure is however modified when lignin is part of composites or gels. 46 In the attempt to gain further information on interactions underpinning the gels, we recorded the FTIR-ATR spectra of polymers, ILs and gels. However, in all cases, the signals of the polymers were covered by the ones of ILs, present in large excess, preventing such information to be gained.…”

Application of Plasticizer Glycerol in Lignosulfonate-Filled Rubber Compounds Based on SBR and NBR

“…The rest is usually incinerated to obtain energy or just landfilled. Lignins have many interesting properties, such as biodegradability, non-toxicity, antimicrobial and antioxidant behavior, high availability, very good adsorption, and adhesion [ 17 , 18 , 19 ]. They are also compatible with several chemical compounds because they contain many reactive sites that enable various substitutive and addition reactions.…”