Likelihood of left main coronary artery compression based on pulmonary trunk diameter in patients with pulmonary hypertension

Mesquita, Sonia M. F.; Castro, Claudia R. P.; Ikari, Nana Miura; Oliveira, Sérgio Almeida de; Lopes, Antônio Augusto

doi:10.1016/j.amjmed.2003.11.015

Cited by 120 publications

(89 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We have been able to demonstrate an intramyocardial bridge of a coronary artery in only one patient. Our experience is in agreement with the clinical literature, considering that only anecdotal cases have been published on LMCA compression by dilated PA in the last two decades[2,3,4]. Mesquita et al [3] were able to describe LMCA compression in only a few patients with a PA diameter greater than 40 mm, and not all of them reached a 70% LMCA compression angiographically.…”

supporting

confidence: 80%

Author’s Reply

Badagliacca¹

2012

Cardiology

View full text Add to dashboard Cite

supporting

confidence: 80%

Author’s Reply

Badagliacca¹

2012

Cardiology

View full text Add to dashboard Cite

“…Despite its common detection, only a small proportion of patients with PH had a diameter >40 mm, a value above which PA dissection has been reported in the literature [3,12,13,14]. Analysis of the relation between PA dilatation and clinical or hemodynamic variables has not found any significant correlation, revealing only a weak correlation with pulmonary mean pressure and RAP.…”

Section: Discussionmentioning

confidence: 90%

Pulmonary Arterial Dilatation in Pulmonary Hypertension: Prevalence and Prognostic Relevance

Badagliacca¹,

Poscia²,

Pezzuto³

et al. 2012

Cardiology

View full text Add to dashboard Cite

Objectives: Pulmonary arterial dilatation is considered a consequence of chronic pulmonary hypertension (PH), but despite its relatively common detection, its prevalence and prognostic impact have not yet been systematically investigated. The aim of the study was to investigate these factors in a relatively large cohort of severe PH patients. Methods: One hundred and forty-one consecutive patients diagnosed with PH were monitored for a mean of 957 days. Data including functional class, exercise capacity, invasive hemodynamics and pulmonary artery (PA) echo/CT scan measurement were performed and outcomes prospectively collected. Results: PA dilatation is a common feature, present in the 76.6% of cases in this cohort of severe PH patients. Survival at 1, 2 and 3 years was 83, 71 and 58%, respectively. On univariate analysis, the baseline variables associated with a poor outcome were related to pulmonary arterial hypertension associated with connective tissue disease (CDT-PAH), New York Heart Association (NYHA) functional class, 6-min walk test and right atrial pressure. On multivariate analysis only CDT-PAH and NYHA functional class remained independently associated with poor survival. Conclusions: PA dilatation is commonly detected in severe PH patients and is not associated with an increased risk of death.

show abstract

“…Of note is that chest pain is reported by over 40% of PAH patients [10] and is typically caused by RV hypoperfusion and demand ischemia resulting from increased RV load [11], pulmonary artery distention with activation of pain receptors [12] and less commonly by LMCA compression by a dilated pulmonary artery. This latter complication is more frequently seen in patients with long standing PAH [5 13] and particularly in subjects with idiopathic PAH [5 7 14], PAH associated with atrial septal defect [13] and chronic thromboembolic pulmonary hypertension [15 16] (Table 1). …”

Section: Discussionmentioning

confidence: 99%

“…Conversely, other locations of the left coronary sinus might be protective and this explains why some patients with very large pulmonary arteries do not develop this complication [17 18]. Furthermore, younger age and female gender appear to be risk factors [13]. However, Mesquita et al [13] found no association between age, gender, PAH etiology and LMCA compression.…”

Section: Discussionmentioning

confidence: 99%

Compression of adjacent anatomical structures by pulmonary artery dilation

Dakkak

Tonelli

2016

Postgraduate Medicine

View full text Add to dashboard Cite

Pulmonary hypertension is the commonest condition leading to dilated pulmonary artery. We describe three different types of compression of adjacent anatomical structures by dilated pulmonary arteries. We included involvement of the left main coronary artery, left recurrent laryngeal nerve and tracheobronchial tree. Compression of these structures can cause major complications such as myocardial ischemia, hoarseness and major airway stenosis. We present a case for each scenario and review the literature for each of these complications, focusing on patients’ characteristics and contemporary management.

show abstract

Likelihood of left main coronary artery compression based on pulmonary trunk diameter in patients with pulmonary hypertension

Cited by 120 publications

References 19 publications

Author’s Reply

Author’s Reply

Pulmonary Arterial Dilatation in Pulmonary Hypertension: Prevalence and Prognostic Relevance

Compression of adjacent anatomical structures by pulmonary artery dilation

Contact Info

Product

Resources

About