Lime (Citrus aurantifolia L.) Juice a Potent Treatment for the Virulent Hepatocarcinogen Aflatoxin B1 in Peanut Paste

Kabbashi, Esameldin Bashir Mohamed; Ali, Salah Eldeen Abbas; Abdel-Rahman, Nawal Abdel-Gayoum

doi:10.5455/jmp.20160413111838

Cited by 3 publications

(2 citation statements)

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“…The results revealed a reduction in AFB 1 of 11 and 31% after treatment with 0.5:1 and 1:1 lime juice (ml): Paste (g) for 1 day, respectively. In addition, the corresponding results after 3 days and 7 days of storage of the abovementioned proportions were 54 and 66% and 74 and 92%, respectively [132].…”

Section: Aflatoxin Treatmentmentioning

confidence: 88%

Major Contaminants of Peanut and Its Products and Their Methods of Management

B.M. Kabbashi

2024

Food Science and Nutrition

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Peanut (Arachis hypogeae L.), Fabaceae, is highly rich in protein (26%). It has popular products such as roasted peanut, peanut butter, and oil. They are vulnerable to many contaminants specified by the Codex Alimentarius, Codex Committee on Contaminants of Food (CCCF), such as biological contaminants, insects, fungi, bacteria, and toxins, which can be byproducts or native contaminants; mycotoxins, which are yard sticks in local and global trade; physical and solid objects (e.g., trash); residues of pesticides and aerial pollutants, such as heavy metals, including lead, copper, nickel, and halogens, etc., from industrial gases and wastes; and industrial byproducts, such as furans and radiation, in addition to the free radicles that arise from rancidity and other metabolic processes. The reactions from and actions taken by the organizations of pertinence are reflected in the setting of maximum acceptable limits (MALs). These include the FAO, WHO, Codex Alimentarius, the European Food Safety Association (EFSA), USA and KSA Food and Drug Administrations, the SSMO (Sudanese Standards & Metrology Organization), etc. However, researchers and governments worldwide are all involved in enormous tedious and fruitful efforts to integrate the management of these contaminants.

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Section: Aflatoxin Treatmentmentioning

confidence: 88%

Major Contaminants of Peanut and Its Products and Their Methods of Management

B.M. Kabbashi

2024

Food Science and Nutrition

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“…Leaf and root extracts were found to show antibacterial effect, fruit juice showed anticancer and antifertility effect, peel extracts possessed antidiabetic, antihyperlipidemic, and antioxidant effects. 8,[10][11][12][13] Literature review demonstrated very little work on methanol extracts of C. aurantifolia peel. As part of our ongoing research on Bangladeshi medicinal plants 4, [14][15][16] and to establish the scientific basis of above stated traditional uses of this plant, the current study was designed to evaluate the antioxidant, antibacterial and cytotoxic potential of the various fractions of methanol extract of C. aurantifolia peel by various in vitro approaches.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant, Antimicrobial and Cytotoxic Activities of Different Fractions of Citrus aurantifolia Peel

Ghosh

Hoque

Shanta

et al. 2020

Dhaka Univ. J. Pharm. Sci

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The present study was designed to investigate antioxidant, antimicrobial and cytotoxic effects of petroleum ether, chloroform and hydromethanol fraction of methanol extract of Citrus aurantifolia peel. Preliminary phytochemical screening of the fractions was done following the standard procedure. Antioxidant activity was measured using DPPH free radical scavenging assay besides measuring total phenolic and flavonoid content using Folin-Ciocalteu reagent and aluminum trichloride method, respectively. The antimicrobial activity was conducted by disc diffusion method and cytotoxic activity was determined by brine shrimp lethality bioassay. The results of phytochemical screening were indicative of the presence of steroids, alkaloids, saponins, glycosides, flavonoids in the fractions. A dose dependent scavenging activity was observed in DPPH radical scavenging assay where chloroform fraction demonstrated the highest activity with IC50 value of 153.68 ± 3.60 μg/ml. The highest phenolic content was observed in chloroform fraction (308.0 ± 6.55 mg/g gallic acid equivalent) and highest flavonoid content was found in hydromethanol fraction (132.66 ± 2.36 mg/g quercetin equivalent). The chloroform fraction showed excellent antibacterial activity against all the tested bacteria where highest zone of inhibition (19 mm) was produced against Bacillus cereus. In brine shrimp lethality bioassay, LC50 values for petroleum ether, chloroform and hydromethanol fractions were 367.39 μg/ml, 228.14 μg/ml and 296.52 μg/ml, respectively. The present findings suggested that C. aurantifolia peel could be a potent source of medicinally important secondary metabolites and further investigations can be done to identify those active compounds responsible for such bioactivity. Dhaka Univ. J. Pharm. Sci. 19(2): 161-168, 2020 (December)

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Use of Natural Dietary Spices for Reclamation of Food Quality Impairment by Aflatoxin

Negera

Washe

2019

Journal of Food Quality

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Certain natural dietary spices, in addition to their use in food flavoring and preservation, have the ability to detoxify or degrade a wide range of chemical carcinogens. In the present study, aqueous extracts of judiciously selected natural dietary spices were evaluated for their ability to degrade aflatoxin B1 (AFB1). A total of 9 spices including garlic (Allium sativum), ginger (Zingiber officinale), black cumin (Nigella sativum), clove (Syzygium aromaticum), sacred basil (Ocimum basilicum), lemon grass (Cymbopogon citratus L. (DC) Stapf)), thyme (Thymus schimperi), fenugreek (Trigonella foenum-graecum), and lemon traditionally used by the Ethiopian Community for food flavoring and preservation were considered. Aflatoxin degradation efficacy of the spice extracts was studied through determination of the toxin in extract-treated and nontreated samples using LC-MS/MS. The degradation was characterized by electrochemical methods based on the characteristic oxidation peak of phenolic hydroxyl resulting from the degradation of the toxin after treatment with the extracts. Of the various spices, garlic showed the highest 35.8% (30 min) to 61.7% (1 hr) in spiked and 46.7% (30 min) to 68.3% (1 hr) and real-sample (contaminated maize) treatment reduction followed by lemon 34.2% (30 min) to 56.0% (1 hr) in spiked and 41.1% (30 min) to 60.6% (1 hr) in real-sample treatment at 25°C. The level of reduction was higher in real-sample treatment than that in spiked. This suggests adsorptive contribution by the matrix in addition to the chemical degradation. The current findings revealed nonobvious benefits of the use of natural dietary spices as effective solution for AFB1 degradation and decontamination of food.

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Lime (Citrus aurantifolia L.) Juice a Potent Treatment for the Virulent Hepatocarcinogen Aflatoxin B1 in Peanut Paste

Cited by 3 publications

References 0 publications

Major Contaminants of Peanut and Its Products and Their Methods of Management

Major Contaminants of Peanut and Its Products and Their Methods of Management

Antioxidant, Antimicrobial and Cytotoxic Activities of Different Fractions of Citrus aurantifolia Peel

Use of Natural Dietary Spices for Reclamation of Food Quality Impairment by Aflatoxin

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