The fatigue strength of components is affected by loading and environmental conditions, their geometry, the material and the manufacturing process adopted for their production. As a consequence of local stress concentrations, fatigue cracks can propagate to failure from the defects created by the manufacturing processes or introduced during the service life, as occurs in impact-damage. Ti6Al4V titanium alloy is commonly used in the aeronautical sector and other engineering applications due to its high specific strength. The study of the fatigue behavior of Ti6Al4V is therefore critical for designing reliable and durable structures. The work reports a synthesis of the results present in the literature for the fatigue behavior of Ti6Al4V in inert and aggressive environments, in the presence of a deposited coating, in the case of impact-damage, when components are produced by additive manufacturing and in the absence of solution treatment and over-aging.