“…Even though the widespread use of brain monitors based on these processed EEG numerical scales constituted a significant advance in brain function monitoring within the practice of anesthesiology, they all have significant limitations. 8,9 To date, with the lack of effective consideration of neurobiologic background that is commonly encountered in these monitors (eg, not taking into account the normal electroencephalographic changes with all ages including changes seen in the elderly, or, the fragile brain of sick patients), there is a strong call to integrate raw EEG and spectral analysis into a broad monitoring strategy that allows the clinician to be aware of the neuroelectrical cerebral activity. By doing so, one can individualize anesthetics dosing while being able to observe the dynamic state of the brain during anesthesia or sedation.…”