Textbook of Pediatric Neurosurgery 2020
DOI: 10.1007/978-3-319-72168-2_110
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Limited Dorsal Spinal Nondisjunctional Disorders: Limited Dorsal Myeloschisis, Congenital Spinal Dermal Sinus Tract, and Mixed Lesions

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“…The pathophysiology of LDM is hypothesized to be a primary neurulation anomaly that results in incomplete disjunction between the cutaneous and neural ectoderms of the developing embryo [2]. Based on their cutaneous manifestations, LDMs are classified as saccular or non-saccular (flat) [1].…”
Section: Introductionmentioning
confidence: 99%
“…The pathophysiology of LDM is hypothesized to be a primary neurulation anomaly that results in incomplete disjunction between the cutaneous and neural ectoderms of the developing embryo [2]. Based on their cutaneous manifestations, LDMs are classified as saccular or non-saccular (flat) [1].…”
Section: Introductionmentioning
confidence: 99%