Linear Accelerator Supervoltage Radiotherapy

Bagshaw, Malcolm A.; Kaplan, Henry S.; Sagerman, Robert H.

doi:10.1148/85.1.121

Cited by 175 publications

(31 citation statements)

References 13 publications

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“…In the late 1950s, pioneering work by Malcolm Bagshaw (FIG. 1d) and others revealed the possibility of radiation curability of prostate cancer 55,56 .…”

Section: Radiation Therapymentioning

confidence: 97%

A history of prostate cancer treatment

2002

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The increased incidence of prostate cancer has led to remarkable changes in diagnosis and treatment over the past century. What were the first ways in which prostate cancer was treated, and how did these evolve into the variety of therapeutic strategies from which patients have to choose today?In 1853, J. Adams, a surgeon at The London Hospital, described the first case of prostate cancer, which he discovered by histological examination 1 . Adams noted in his report that this condition was "a very rare disease". Remarkably, 150 years later, prostate cancer has become a significant health problem. In the United States, it is the most commonly diagnosed cancer in men, with 180,000 new cases and about 31,000 deaths occurring annually 2 . This dramatic increase in the number of prostate cancer cases can be attributed to several causes. First, prostate cancer was not differentiated from other types of urinary obstruction until the early 1900s. Second, the incidence of prostate cancer increases more rapidly with age than any other cancer type 2 . The number of cases has risen as the average life expectancy has increased over the past century. Third, the increased incidence seems to be, in some way, related to the 'Western' lifestyle: the incidence of clinical prostate cancer is significantly lower in Asian populations, compared with Western populations 3 , and it

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“…In the late 1950s, pioneering work by Malcolm Bagshaw (FIG. 1d) and others revealed the possibility of radiation curability of prostate cancer 55,56 .…”

Section: Radiation Therapymentioning

confidence: 97%

A history of prostate cancer treatment

2002

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show abstract

“…In 1956 megavoltage external-beam radiation therapy was introduced and became the preferred radiotherapeutic management for localized prostate cancer. 4,5 In 1972 an open-surgical, retropubic brachytherapy method with permanent implants used for the radiation source was introduced by Whitmore et al 6 at Memorial Sloan-Kettering using iodine 125 and by Carlton et al 7 using gold 198 in combination with external-beam radiation therapy (Fig. 1).…”

Section: Historical Backgroundmentioning

confidence: 99%

Brachytherapy for prostate cancer

Porter

Blasko

Grimm³

et al. 1995

CA: A Cancer Journal for Clinicians

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“…External-beam irradiation has been given for the treatment of carcinoma of the prostate since the 1930s [1]. Bagshaw et al [1] in Stanford were the first to describe radical radiotherapy in 1965; the group initially recorded an actuarial survival at 5 years of 54%.…”

Section: Introductionmentioning

confidence: 99%

“…Bagshaw et al [1] in Stanford were the first to describe radical radiotherapy in 1965; the group initially recorded an actuarial survival at 5 years of 54%. The figures quoted for 5-year survival range from 29 to 90%, depending on the stage [2][3][4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%