Linear and cyclic poly(2-isopropyl-2-oxazoline)s for fine control of thermoresponsiveness

A new thermoresponsive polymer of poly(N-acryloylsarcosine methyl ester) with a tunable LCST

“…[1][2][3] Amongst the thermoresponsive polymers, an abundance of macromolecules exhibiting a lower critical solution temperature (LCST) with a coil-to-globule transition in water solution, are probably the most investigated. To date, the LCSTtype thermoresponsive polymers can be summarized into six categories: poly[oligo(ethylene glycol) (meth)acrylate]s, [5][6][7] poly(2alkyl-2-oxazoline)s, 8,9 poly(vinyl methyl ether)s, 10,11 polypeptides, [12][13][14] N-alkyl-substituted poly(aminoethyl methacrylate)s, [15][16][17][18] and especially N-substituted poly(meth)acrylamides with a pendant of amide group. Recently, many kinds of technologies have verified that the amide pendant of polyacrylamide plays key role in forming hydrogen bonding with water or the additives (e.g.…”

Next‐Generation Polymer Shells for Inorganic Nanoparticles are Highly Compact, Ultra‐Dense, and Long‐Lasting Cyclic Brushes

“…[37,38] As reported in Figure 3, NPs dispersed in PBS were heated from 20 to 70 8 8C, and the values of D H were simultaneously recorded by DLS.W hile L-and l-PEOXA-NPs underwent aggregation starting from approximately 55 8 8C, C-and c-PEOXA-NPs showed an increase in the aggregation temperature of around 10 8 8C, with adistinct onset at approximately 65 8 8C. [39] In the case of linear PEOXA-NPs the aggregation process was irreversible,a nd the NPs were not redispersed into single NP suspensions after decreasing…”

Phototunable Cloud Point Temperatures Stemming from Cyclic Topology: Synthesis and Thermal Phase Transition Behavior of Cyclic Poly(N‐acryloylsarcosine methyl ester)

“…Thermoresponsive polymer with lower critical solution temperature (LCST) which exhibits a transition between hydrated and dehydrated states when the temperature is altered, has drawn considerable attention because of its potential applications in surface modification, [1] drug delivery, [2] and supports for cell culture, [3] etc. Examples of LCST-type polymer contain poly(N-isopropylacrylamide) (PNIPAM), [4][5][6] poly(2-isopropyl-2-oxazoline) (POx), [7] poly(N-acryloylsarcosine methyl ester) (PNASME), [8] to list only a few. PNIPAM is the most commonly and substantially studied thermoresponsive polymer because its LCST (≈32°C) is near the range of the physiological temperature, which provides the possibility for its biotechnological DOI: 10.1002/marc.202100136 applications.…”