Linear GoId(I) Derivatives with Bulky Phosphine and Imidazolato Ligands. X-Ray Crystal Structure of 1-(C₆H₁₁)₃PAu-2-i-Pr-Imidazole · C₆H₆

Abstract

<jats:p>By reaction of a 1-unsubstituted imidazole (im H) with alkali and R<jats:sub>3</jats:sub>′PAuCl under phase transfer conditions or in MeOH solution R<jats:sub>3</jats:sub>′PAu (im-N) compounds were obtained where R′ = C<jats:sub>6</jats:sub>H<jats:sub>11</jats:sub> or t-Bu, and imH was imidazole, 2-i-Pr-, 4-NO<jats:sub>2</jats:sub>-imidazole or benzimidazole. When the Ph<jats:sub>3</jats:sub>Sb (or Ph<jats:sub>3</jats:sub>As) homologue was reacted, polymeric [μ-(2-methylimidazolato-N,N′)gold(I)]<jats:sub>n</jats:sub> was obtained, together with (Ph<jats:sub>3</jats:sub>Sb)<jats:sub>2</jats:sub>AuCl.</jats:p><jats:p>The X-ray crystal structure of 1-[(C<jats:sub>6</jats:sub>H<jats:sub>11</jats:sub>)<jats:sub>3</jats:sub>PAu]-2-i-Pr-imidazole confirmed that the gold atom is linearly coordinated (177.0(1)°), with Au - N 2.019(5) and Au -P 2.255(2) Å .</jats:p>

Bis(4-hydroxymethyl-1,5-dimethylimidazole-N3)gold(I) chloride

“…The bond lengths and angles within the rings are remarkably uniform; there is little indication of single bond-double bond localization. They agree well with values for various imidazoles summarized by Bovio et al (1984).…”

“…The rings attached to the Au atom are arranged such that the cation has very approximate C2h symmetry, although this is destroyed by the disorder of the O atoms attached to C(41'). As such, the cation is roughly planar; the imidazole rings are at 12.4 ° to each other, which is achieved by the rings twisting about the N(3)-..N(3') axis rather than the cation bending at the The Au--N bond lengths [Au--N(3) 2.011 (5), Au--N(3') 2.000 (5)/~] are shorter than the values quoted for similar Au ~ compounds, although the large errors in most previous determinations mean there is no significant difference (Bovio, Bonati, Burini & Pietroni, 1984;Adams, Hiller & Str~ihle, 1982;Fehlhammer & Finck, 1991). The distances observed here are even shorter than the Auln--N distances in the dimethyl(tri-2-pyridylmethane-N,N')gold(III) cation (Canty, Minchin, Healy & White, 1982), although they are longer than the Aum--N distances in trichloropyridinegold(III) and the dichlorodi(pyridine)gold(III) cation (Adams & Strfihle, 1982).…”

First Crystal Structure of a Medicinally Relevant Gold Protein Complex: Unexpected Binding of [Au(PEt3)]+ to Histidine

“…This was interpretable as PEt 3 as indicated by the shape of the electron density. The structure was refined with SHELXL97 [14] using 20 154 unique data (5 % for the calculation of R free ) and initial constraints on the Au À N and AuÀP bond lengths of 2.05 and 2.27 , respectively, values similar to those in crystalline [Au(2-isopropylimidazole)(Pcy 3 )] [15] and [Au(phthalimido)(PEt 3 )] [16] . The final R factor was 18.48 % and R free 24.68 %.…”

Mono- and Binuclear Gold(I) Compounds Containing Deprotonated Purines and Pyrimidines

“…: l-(triphenylphosphinegold)-6-methyl-2-pyridone [7] or l-tri(cyc/o-hexyl)phosphinegold-2-/so-propylimidazole [8]. The ligand L is triphenylphosphine for several reasons: the starting compound LAuCl is easily obtained and handled, the corresponding products are generally soluble in organic solvents, and the A u -P bond is not as easily broken as, for example, the A u -As or the A u -Sb bond of similar compounds having triphenylarsine or triphenylstibine in the place of L [8,11].…”

“…These were found to be stable and soluble in organic solvents, thus allowing spectroscopic investigations, whereas the uncomplexed gold(I) derivatives are often insolu ble coordination polymers or, at best, oligomers, e.g. : l-gold-2-R-imidazole (R = /so-proypl [8] or phenyl [9]) and tris(pyrazolato-N,N')trigold(I) [10], respectively.…”