High‐efficiency quantum information processing is equivalent to the fewest quantum resources and simplest operations by means of logic qubit gates. Based on the reflection geometry of a single photon interacting with a three‐level Λ‐type atom‐cavity system, the authors present some refined protocols for realizing controlled‐not (CNOT), Fredkin, and Toffoli gates on hybrid systems. The first control qubit of gates is encoded on a flying photon, and the remaining qubits are encoded on the atoms in the optical cavity. Moreover, these quantum gates can be extended to the optimal synthesis of multi‐qubit CNOT, Fredkin, and Toffoli gates with optical elements without auxiliary photons or atoms. Further, the simplest single‐qubit operations are applied to the photon only, which make these logic gates experimentally feasible with current technology.