Background: The Ethiopian highlands are affected by soil loss caused by soil erosion resulted in soil properties deterioration. To reverse this, different soil and water conservation (SWC) measures were spatially practiced; however, the effect of SWC and slope gradient on soil properties is not studied well in the area. Hence, this study was conducted to evaluate the effects of SWC and slope gradient on selected soil physicochemical properties at Dawnt watershed, North-western Ethiopia. The treatments were a combination of four different SWC measures with three slope gradients replicated at three sites. Disturbed and undisturbed soil samples were collected from 0-20cm soil depth and physicochemical properties were determined following standard laboratory procedures. Results: The lab results depict that sand, bulk density, moisture, particle density, porosity, pH, organic carbon (OC), cation exchange capacity (CEC), total nitrogen, and available phosphorus were significantly (P<0.05) affected by SWC measures and slope gradient. High OC (2.44%), CEC (45cmol (+) kg-1), and moisture (19.55%) were obtained from Stone-Faced Soil Bund stabilized with Grass (SFSBG) and high available phosphorus (7.83ppm) from Soil Bund (SB) while lower bulk density (1.13gm/cm3) from SFSBG. Additionally, higher clay (41.67%) and moisture (19.81%) and lower bulk density (1.14g/cm3) were obtained from the lower slope. Higher pH (6.75) and OC (2.89%) were recorded at lower slope under SFSBG and lower pH and OC (6.03 and 1.02%) at the upper slope with non-conserved. Soil chemical properties, except available potassium, were increased down the slope.Conclusion: The interactions of slope position and SWC measures affect soil texture; pH, organic carbon, and available phosphorus but do not affect soil bulk density, moisture content, particle density, total porosity, cation exchange capacity, total nitrogen, and available potassium. In generally, the soil properties were improved through integrating conservation practices with multipurpose grass species across the study watershed. Therefore, in the study watershed and other similar agro-ecologies, farmers should use integrated SWC measures to avert the rainfall-driven soil nutrient loss.